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tags or marker sequences

Russian translation: таги или маркерные последовательности

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11:12 Apr 18, 2005
English to Russian translations [PRO]
Medical - Medical (general)
English term or phrase: tags or marker sequences
The present invention also encompasses antibodies or antigen-binding fragments thereof that preferentially bind to cell-associated CA 125/O772P fused to marker sequences, such as a peptide to facilitate purification. For example, a marker amino acid sequence can be a hexa-histidine peptide, such as the tag provided in a pQE vector (QIAGEN, Inc., 9259 Eton Avenue, Chatsworth, CA, 91311), among others, many of which are commercially available. As described in Gentz et al., Proc. Natl. Acad. Sci. USA. 86(3):821-824 (1989), for instance, histidine, e.g., hexa-histidine, provides for convenient purification of the fusion protein. Other peptide tags useful for purification include, but are not limited to, the hemagglutinin "HA" tag, which corresponds to an epitope derived from the influenza hemagglutinin protein (Wilson et al., Cell. 37(3):767-778 (1984)) and the "flag" tag (Brizzard et al., Biotechniques. 16(4):730-735 (1994)). Preferably, such ***tags or marker sequences*** are cleaved from the fusion polypeptide prior to use, e.g., use as part of a therapeutic method.

Подозреваю, что "метки или маркерные последовательности"???
Local time: 20:49
Russian translation:таги или маркерные последовательности
См. вопрос про tags
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Local time: 19:49
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4таги или маркерные последовательности



1 day 23 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
таги или маркерные последовательности

См. вопрос про tags

Local time: 19:49
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