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English to Russian translations [PRO] Medical - Medical (general) / immunihistochemistry
English term or phrase:pan (as in pan keratin cocktail)
***Anti-Pan Keratin Primary Antibody*** may be used to aid in the identification of normal and abnormal epithelial cells and to determine the lineage of poorly differentiated malignant tumors.
Nineteen human cytokeratins are known which are divided into acidic and basic subfamilies. They occur in pairs in epithelial tissues, the composition of pairs varying with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. This ***pan keratin cocktail*** recognizes most of the acidic and all of the basic cytokeratins, making it a useful stain for nearly all epithelial tissues and their tumors.
Марина, приставка "пан" здесь употреблена в таком же смысле, как, скажем, в слове "пан-американский". Панкератин - это смесь многих видов кератина, а анти-панкератиновые антитела реагируют как на кислые, так и на основные кератины, т.е. являются весьма
Automatic update in 00:
1 hr confidence:
смесь антител к кератинам
Explanation: Pathologists use antibodies - a protein fragment that will attach to certain tissues - to determine if a type of tissue is present. This helps them know the source of the tumor and in some cases can tell the oncologist how to treat the tumor. ***Pankeratin is a mixture of antibodies that detect multiple types of keratin in a single test, rather than using a test for a single keratin.***
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Pavel Nikonorkin Local time: 08:54 Specializes in field Native speaker of: Russian PRO pts in category: 1479