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anti-product antibodies (APA)

Russian translation: антитела к продукту / антихимерные антитела (АХА)

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:anti-product antibodies (APA)
Russian translation:антитела к продукту / антихимерные антитела (АХА)
Entered by: Olga Pinchuk
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18:53 Sep 11, 2011
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: anti-product antibodies (APA)
HACA (also referred to as APA)=human anti-chimeric antibody (anti-product antibodies)
Прочитала, что human anti-chimeric antibody это "человеческие антихимерные антитела".

Спасибо за помощь!
Olga Pinchuk
Ukraine
Local time: 11:26
антитела к продукту / антихимерные антитела (АХА)
Explanation:
Если продукт - это химерное антитело (например, инфликсимаб), то в ответ на его введение в организме вырабатываются другие антитела, по сути, антитела к химерным антителам; да, действительно, их называют "антихимерными".

Примеры:
Chimeric antibodies such as IFX induce human anti-chimeric antibodies (HACA), also referred to as antibodies-to-infliximab (ATI).
http://www.practicalgastro.com/pdf/October10/CassinottiArtic...

Антихимерные антитела (АХА)
АХА (Human AntiChimeric Antibody, HACA) антитела – антитела к РМ определяются значительно чаще при лечении СКВ [61], чем в терапии лимфом...
http://www.reumo.ru/portal/synergy/static/file/synergy/alfpr...
Selected response from:

Natalie
Poland
Local time: 10:26
Grading comment
4 KudoZ points were awarded for this answer

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Summary of answers provided
4 +3антитела к продукту / антихимерные антитела (АХА)
Natalie


  

Answers


19 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
anti-product antibodies (apa)
антитела к продукту / антихимерные антитела (АХА)


Explanation:
Если продукт - это химерное антитело (например, инфликсимаб), то в ответ на его введение в организме вырабатываются другие антитела, по сути, антитела к химерным антителам; да, действительно, их называют "антихимерными".

Примеры:
Chimeric antibodies such as IFX induce human anti-chimeric antibodies (HACA), also referred to as antibodies-to-infliximab (ATI).
http://www.practicalgastro.com/pdf/October10/CassinottiArtic...

Антихимерные антитела (АХА)
АХА (Human AntiChimeric Antibody, HACA) антитела – антитела к РМ определяются значительно чаще при лечении СКВ [61], чем в терапии лимфом...
http://www.reumo.ru/portal/synergy/static/file/synergy/alfpr...

Natalie
Poland
Local time: 10:26
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 8118
Notes to answerer
Asker: Спасибо за помощь!


Peer comments on this answer (and responses from the answerer)
agree  Ivan Borshchevsky
9 hrs

agree  tatyana_k
10 hrs

agree  Yana Onikiychuk
2 days 11 hrs
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