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non-deformable MR formulation technology

Russian translation: объяснительно

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15:44 Oct 12, 2017
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: non-deformable MR formulation technology
Section 4.4 Special warnings and precautions for use:

this section has been modified to include maximum dosing recommendations for the modified release (MR) osmotic tablet formulation of tofacitinib in rheumatoid arthritis (RA) patients with renal impairment and hepatic impairment.

Section 4.4 has also been modified to include the addition of a warning for patients with pre-existing severe gastrointestinal (GI) narrowing based on reports of obstructive symptoms associated with ingestion of other drugs utilizing a *non-deformable MR formulation technology*.

2.5.1. Product Development Rationale

Tofacitinib (XELJANZ, CP-690,550) is a potent, selective inhibitor of the Janus kinase (JAK) family of kinases with a high degree of selectivity against other kinases in the human genome.
Maxim Polukhin
Local time: 17:12
Russian translation:объяснительно
Explanation:
технология обеспечения модифицируемого выделения активного вещества из таблетки в условиях желудочно-кишечного тракта (non-deformable, т.е. техология препятствует изменению выделения под влиянием среды жкт)
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fromBishkek
Kyrgyzstan
Local time: 20:12
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3объяснительноfromBishkek


  

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2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
non-deformable mr formulation technology
объяснительно


Explanation:
технология обеспечения модифицируемого выделения активного вещества из таблетки в условиях желудочно-кишечного тракта (non-deformable, т.е. техология препятствует изменению выделения под влиянием среды жкт)

fromBishkek
Kyrgyzstan
Local time: 20:12
Native speaker of: Native in RussianRussian
PRO pts in category: 45
Grading comment
Спасибо!
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