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pyloric junction

Russian translation: в месте соединения с пилорическим отделом желудка

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06:13 Feb 6, 2018
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: pyloric junction
Gastroduodenal Proliferations

Gastroduodenal or duodenal carcinoma, accompanied by hyperplasia of Brunner’s glands or gastric mucosa, was observed in hemizygous rasH2 transgenic mice in studies of 1- and 6-month duration or Sprague-Dawley rats in a 2-year carcinogenicity assessment.

In the 1-month range-finding study, carcinoma of the Brunner’s gland, located in the duodenal submucosa at the pyloric junction, was observed in emizygous rasH2 transgenic mice at 200 mg/kg/day (Table 2.6.7.10A, Study 2005-0088).

The carcinoma was observed in 2 female mice, one of which was found dead on Day 26 and the other was 1 of 2 main study animals that survived to term.

Hyperplasia of Brunner’s glands and gastric mucosal hyperplasia were also observed at 200 mg/kg/day.

Systemic exposure at 200 mg/kg/day was not defined due to excessive mortality in the TK satellite groups (wild type and hemizygous).
Maxim Polukhin
Local time: 15:13
Russian translation:в месте соединения с пилорическим отделом желудка
Explanation:
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Note added at 41 мин (2018-02-06 06:54:41 GMT)
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или на границе с пилорическим отделом желудка

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Note added at 44 мин (2018-02-06 06:57:29 GMT)
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Еще варианты: в области пилородуоденального перехода (соединения)
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Doctor Alex
Local time: 15:13
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4в месте соединения с пилорическим отделом желудка
Doctor Alex


  

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40 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
в месте соединения с пилорическим отделом желудка


Explanation:
.

--------------------------------------------------
Note added at 41 мин (2018-02-06 06:54:41 GMT)
--------------------------------------------------

или на границе с пилорическим отделом желудка

--------------------------------------------------
Note added at 44 мин (2018-02-06 06:57:29 GMT)
--------------------------------------------------

Еще варианты: в области пилородуоденального перехода (соединения)

Doctor Alex
Local time: 15:13
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 651
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