Login or register (free and only takes a few minutes) to participate in this question.
You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.
English to Spanish translations [PRO] Science - Medical: Pharmaceuticals / Assay
English term or phrase:icilin
1 TRPM8 (CMRI) is a Ca2-permeable channel, which can be activated by low temperatures, menthol, eucalyptol and **icilin**. It belongs to the transient receptor potential (TRP) family, and therefore is related to vanilloid receptor type-! (VRI, TRPVI).
Explanation: Hola Sandra,
Tal vez esta información te sea de alguna utilidad en lo que damos con el nombre en español:
"***Icilin also known as AG-3-5, chemical name 1-[2-hydroxyphenyl]-4-[2-nitrophenyl- ]-1,2,3,6-tetrahydropyrimidine-2-one***) was discovered in 1983 to produced sensations of coldness when in contact with mucous membranes (nostrils, lips and eyelids) of the researchers, and also when ingested (see Wei et al, J. Pharm. Pharmacol. 1983, 35:110-112). It is recognized that Icilin is a considerably more potent coolant than menthol. It is a super agonist that is 2.5-fold more efficacious and nearly 200-fold more potent than the reference cold thermosensory agonist, l-menthol ..."