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  3. Medical: Pharmaceuticals

offset

Spanish translation: neutralizar

16:50 Nov 24, 2008
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / Estudios clínicos
English term or phrase: offset
¿Cuál es el significado de offset en este contexto?

"To characterize the pharmacokinetics of ABC in the presence and absence of XXX and to determine the offset of any effect of XXX on ABC disposition....

After an 10-day washout, ABC dosing and blood sampling were repeated to evaluate the offset of any potential interaction."

Como siempre, gracias por su enorme ayuda :)
Spring Moon
Local time: 18:51
Spanish translation:neutralizar
Explanation:
creo que es lo que quiere decir quí
Selected response from:

cebice
United States
Local time: 18:51
Grading comment
Finalmente opté por neutralización. Muchas gracias.
3 KudoZ points were awarded for this answer



Summary of answers provided
4 +2neutralizar
cebice
4 +1desplazamiento/desplazo
Gilberto Diaz Castro
5 -1inicio
Marta Cervera Areny
4desaparición
aforgas


  

Answers


4 mins   confidence: Answerer confidence 5/5 peer agreement (net): -1
inicio


Explanation:
Yo lo diría así

Marta Cervera Areny
Spain
Local time: 01:51
Specializes in field
Native speaker of: Native in CatalanCatalan, Native in SpanishSpanish
PRO pts in category: 8

Peer comments on this answer (and responses from the answerer)
agree  María T. Vargas
1 min
disagree  Marisa Condurso de Nohara: Disculpe colega: inicio = onset (p. ej.: rapid onset of action) rápido inicio de acción/rápida acción
1 hr
disagree  Andrea Riffo: Concuerdo con McNohara; además, tampoco tendría sentido en el contexto de la oración.
1 day 27 mins
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19 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
desaparición


Explanation:
I suppose they are evaluting rsults of a treatment

aforgas
Argentina
Local time: 20:51
Native speaker of: Native in SpanishSpanish
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1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +2
neutralizar


Explanation:
creo que es lo que quiere decir quí

cebice
United States
Local time: 18:51
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 6
Grading comment
Finalmente opté por neutralización. Muchas gracias.
Notes to answerer
Asker: Entonces en este caso sería "neutralización"???


Peer comments on this answer (and responses from the answerer)
agree  Roberto Rey
13 mins
  -> gracias
agree  Marisa Condurso de Nohara: Absolutamente de acuerdo; al neutralizarlo no podrá actuar/tener efecto (antónimo de onset como verbo)
35 mins
  -> gracias
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6 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
desplazamiento/desplazo


Explanation:
Indica que se quiere verificar si XXX desplazará los efectos de ABC en el paciente. De ser así hay que modificar las dosis para recompensar la diferencia.

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Note added at 9 hrs (2008-11-25 02:00:00 GMT)
--------------------------------------------------

http://en.wiktionary.org/wiki/offset


Gilberto Diaz Castro
United States
Local time: 19:51
Native speaker of: Native in EnglishEnglish, Native in SpanishSpanish
PRO pts in category: 20

Peer comments on this answer (and responses from the answerer)
agree  Eloi Castellví Alonso: "Agree", pero creo que se dice "compensar". "Recompensar" es "to reward".
8 hrs
  -> Gracias.
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