12:37 Apr 25, 2018 |
English to Spanish translations [PRO] Medical - Medical: Pharmaceuticals | |||||||
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| Selected response from: George Simon Hungary Local time: 14:40 | ||||||
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3 | uniòn a tejido diana/uniòn a diana |
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3 | interacción con moléculas diana |
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uniòn a tejido diana/uniòn a diana Explanation: From the context given it seems to me that it refers to protein biomarkers which engage or unite with their target in the presence of heart failure. Wether the target is a cell that has been compromised due to heart failure or a part of the cell structure is beyond the context. Reference: http://www.revespcardiol.org/es/biomarcadores-medicina-cardi... |
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interacción con moléculas diana Explanation: Target engagement, en este contexto, parece constituir una expresión ad hoc en referencia a la interacción de determinadas moléculas con objetivos o dianas proteicas en organismos vivos. Por ejemplo, Alternative assays must be enlisted to confirm that a small molecule interacts with its intended protein target in a living system, a parameter that is referred to as target engagement. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004587/ Así, por ejemplo, ... con el propósito de analizar estos biomarcadores proteicos [¿exploratorios? No estoy seguro de a qué se refiere exploratory aquí para plantear una traducción] adicionales relacionados con la modulación de la función cardíaca y con su interacción con moléculas diana en la insuficiencia cardíaca. |
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