recherche de déficit

English translation: Testing for DPD deficiency

06:44 Mar 23, 2019
French to English translations [PRO]
Medical - Medical (general) / DPD deficiencies
French term or phrase: recherche de déficit
The context is as follows:

Recherche de déficit en DPD en vue de prévenir certaines toxicités sévères survenant sous traitement comportant des fluoropyrimidines

What is recherche in this case? Is it search or should it be testing or screening for DPD deficiencies?
Any ideas appreciated.
Valerie Scaletta
Italy
Local time: 22:37
English translation:Testing for DPD deficiency
Explanation:
https://www.cancerresearchuk.org/about-cancer/cancer-in-gene...

Testing for DPD deficiency
At the moment, people having fluorouracil or capecitabine do not have routine testing for DPD before their treatment.

There are tests available, but they are not completely reliable. For instance, they do not find everyone who is likely to have serious side effects. For a test to become standard it needs to be:

accurate
quick
easy to do
cost effective
You might have the test through the NHS if your doctor thinks you need it. For example, if you are having treatment with fluorouracil or capecitabine and you have severe side effects. Some clinics offer this test privately. But we are not able to recommend any one clinic.

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Note added at 2 hrs (2019-03-23 09:37:26 GMT)
--------------------------------------------------

https://academic.oup.com/annonc/article/28/6/1399/3074042

DPD testing must remain a recommended option, but not a recommended routine test
G. Milano
Selected response from:

Sue Davis
France
Local time: 22:37
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1Testing for DPD deficiency
Sue Davis


  

Answers


1 hr   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
Testing for DPD deficiency


Explanation:
https://www.cancerresearchuk.org/about-cancer/cancer-in-gene...

Testing for DPD deficiency
At the moment, people having fluorouracil or capecitabine do not have routine testing for DPD before their treatment.

There are tests available, but they are not completely reliable. For instance, they do not find everyone who is likely to have serious side effects. For a test to become standard it needs to be:

accurate
quick
easy to do
cost effective
You might have the test through the NHS if your doctor thinks you need it. For example, if you are having treatment with fluorouracil or capecitabine and you have severe side effects. Some clinics offer this test privately. But we are not able to recommend any one clinic.

--------------------------------------------------
Note added at 2 hrs (2019-03-23 09:37:26 GMT)
--------------------------------------------------

https://academic.oup.com/annonc/article/28/6/1399/3074042

DPD testing must remain a recommended option, but not a recommended routine test
G. Milano

Sue Davis
France
Local time: 22:37
Meets criteria
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 880

Peer comments on this answer (and responses from the answerer)
agree  Megan Speakman
5 hrs
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