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échappement thérapeutique

English translation: non-response to therapy

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17:35 Feb 1, 2001
French to English translations [PRO]
Medical
French term or phrase: échappement thérapeutique
Bone scan mentions: "la fixation osseuse est beaucoup plus irrégulière: échappement thérapeutique? ou critère de bonne réponse au traitement de lésion secondaire latente?
sktrans
English translation:non-response to therapy
Explanation:
Here's how I understand it:

non-response to therapy? or criteria of positive responsiveness to treatment of latent secondary lesion?
Selected response from:

AVST
United States
Local time: 14:03
Grading comment
Merci à tous ceux qui ont répondu. Votre réponse est arrivée en premier et ma traduction était urgente (laquelle ne l'est pas?).
Ybroad, j'avais au départ choisi "escape" mais sans références pour confirmation. Merci
3 KudoZ points were awarded for this answer

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Summary of answers provided
naineffective treatment/therapy
Lisanne
natherapy escape (phenomenon)
Yolanda Broad
nanon-response to therapyAVST


  

Answers


38 mins
non-response to therapy


Explanation:
Here's how I understand it:

non-response to therapy? or criteria of positive responsiveness to treatment of latent secondary lesion?


    own knowledge
AVST
United States
Local time: 14:03
PRO pts in pair: 14
Grading comment
Merci à tous ceux qui ont répondu. Votre réponse est arrivée en premier et ma traduction était urgente (laquelle ne l'est pas?).
Ybroad, j'avais au départ choisi "escape" mais sans références pour confirmation. Merci
Login to enter a peer comment (or grade)

15 hrs
therapy escape (phenomenon)


Explanation:
Appears to have to do with allergic/immune responses. Here are some entries on "échappement" from Termium:

French: échappement
English:Immune Responses
escape s CORRECT
EX - The escape of the [HIV] virus from the host immune defenses. s
1998-05-15

French: échappement allergique
English:Immune Responses
allergic breakthrough s
CONT - It is evident that a number of factors must contribute to allergy and this has led to the hypothesis of allergic breakthrough, where clinical symptoms of allergy are only seen when an arbitrary level of immunological activity (allergic breakthrough) is exceeded. This will depend on a number of conditions, including exposure to allergen, genetic predisposition, the tendency to make IgE, and other factors, such as the presence of upper respiratory tract viral infections, decreased suppressor activity or transient IgA deficiency. s
1993-02-10

French: échappement immunitaire
English:Immune Responses
immunological escape s
CONT - Mechanisms of immunological escape address the central paradox of tumour immunology which is why neoplasms which are demonstrably immunogenic elude the effector arm of the immune response. Immunological escape may occur when the balance between factors favouring tumour growth and destruction is tilted in favour of the tumour. ... The factors that may contribute to immunological escape include tumour kinetics, antigenic modulation, antigen masking, blocking factors, tolerance, genetic factors, tumour products, and growth factors. s
1993-02-10

Here are a couple of entries I picked up on Google:

Junctional nonunion was seen in five patients (9%), two of whom were treated successfully with bone grafting and bone grafting and plating, respectively. Instability was observed in six patients
(11%). Trochanteric nonunion was seen in 22 patients (43%) and trochanteric escape was seen in 14 patients (27%).


AIO - Abstracts 3.480 - 3.501
... on TRAP mRNA levels. The 'escape phenomenon' may result from reduced ... on the dose and duration of therapy. ... donor alleviates ovariectomy-induced bone loss. ...
"A recently discovered property of calcitonin is the "escape" phenomenon, which is characterized by refractoriness to the effects of the hormone during continuous or prolonged treatment. This phenomenon is caused by a down regulation of calcitonin receptors found in bone and other tissues. Calcitonins used in clinical practice are available from human (recombinant) and salmon origins; calcitonins are also available as intranasal and parenteral dosage formulations." www.osteovision.ch/aio/v3-n2/V3_0480-0501.html



    Reference: http://www.termium.com
    Google searches
Yolanda Broad
United States
Local time: 16:03
Native speaker of: English
PRO pts in pair: 1551
Login to enter a peer comment (or grade)

19 hrs
ineffective treatment/therapy


Explanation:
See the following entry of a medical glossary in French:

ECHAPPEMENT
Se dit lorsqu’un traitement n’est plus efficace...

(http://perso.club-internet.fr/tcasse/glossaire/glossaireaccu...


See also:

... X-rays and/or a bone scan. Early identification is critical to prevent progression and prevent long-term ineffective treatment. The common practice of treating ...
(http://www.oagr.com/JRE_LOWBACKPAIN.htm)


... Effective Clinical Practice. EDITORIAL. Aromatherapy: Ineffective Treatment or Effective Placebo? ...
(http://www.acponline.org/journals/ecp/julaug00/aromatherapy_...


... Shark Cartilage is an Ineffective Cancer Treatment, Study Concludes ZION, Ill.,
May 23, 1997 -- Shark cartilage is not an effective treatment for advanced ...
(http://www.pslgroup.com/dg/2981a.htm)





    Reference: http://perso.club-internet.fr/tcasse/glossaire/glossaireaccu...
Lisanne
Local time: 22:03
Native speaker of: Native in GermanGerman
PRO pts in pair: 16
Login to enter a peer comment (or grade)




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