bloc

English translation: cycle

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

French term or phrase:	bloc
English translation:	cycle

01:32 Mar 7, 2018

The asker opted for community grading. The question was closed on 2018-03-10 19:54:08 based on peer agreement (or, if there were too few peer comments, asker preference.)

French to English translations [PRO]
Medical - Medical (general) / Drug prescription

French term or phrase: bloc

Hi,

The patient suffers from multiple myeloma and received during the hospitalization "un bloc DEXAMETHASONE 20 g/jour pendant 8 jours" followed by chemotherapy.

How would you translate "bloc" in this context?

Thanks

Joanna

joanna menda KudoZ activity Questions: 990 (6 open) (3 without valid answers) (110 closed without grading) Answers: 3 Canada
Local time: 04:20

cycle

Explanation:
See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077090/ and many other sites that use "cycle" or treatment with DEXAMETHASONE.

Selected response from:

Marco Solinas
Local time: 01:20

Grading comment

Thanks Marco! I have finally gone with cycle as my target audience is the US, but Lorraine is also correct as "block" is used in Canada (Thanks Lorraine!)
4 KudoZ points were awarded for this answer

Summary of answers provided

2 +3

cycle

Marco Solinas

blockade

Drmanu49

course

Anne Schulz

block

Lorraine Dubuc

Summary of reference entries provided

nerve block or nerve blockade

liz askew

Discussion entries: 1

Answers

39 mins confidence:

blockade

Explanation:
Stress-induced release of prolactin: blockade by dexamethasone and ...
https://www.ncbi.nlm.nih.gov/pubmed/6244573 - Traduire cette page
de J Rossier - ‎1980 - ‎Cité 156 fois - ‎Autres articles
Stress-induced release of prolactin: blockade by dexamethasone and naloxone may indicate beta-endorphin mediation. Rossier J, French E, Rivier C, Shibasaki T, Guillemin R, ... Morphine (20 mg/kg) also increases ir-beta-endorphin, ACTH, and PRL levels. Dexamethasone pretreatment blocks the morphine-induced ..

Drmanu49
France
Local time: 10:20
Specializes in field
Native speaker of:

English,

French
PRO pts in category: 5346

1 hr confidence:

peer agreement (net): +3

cycle

Explanation:
See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077090/ and many other sites that use "cycle" or treatment with DEXAMETHASONE.

Marco Solinas
Local time: 01:20
Native speaker of:

English,

Italian
PRO pts in category: 103

Grading comment

Thanks Marco! I have finally gone with cycle as my target audience is the US, but Lorraine is also correct as "block" is used in Canada (Thanks Lorraine!)

13 hrs confidence:

course

Explanation:
...to expand the range of options :-)

Anne Schulz
Germany
Local time: 10:20
Specializes in field
Native speaker of: German
PRO pts in category: 237

26 mins confidence:

block

Explanation:
Traitement du médicament, le bloc correspond au nombre de jours comme on dit en anglais 'a block of 8 days' donc je crois que c'est à cela que correspond le mot bloc et non au médicament proprement dit.

Blocks can be 2,5 or 8 days

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Note added at 13 heures (2018-03-07 15:20:10 GMT)
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«On administre habituellement la chimiothérapie d’intensification différée de 3 à 4 mois après que l’enfant ait atteint la rémission à la suite d’une chimiothérapie d’induction. La phase d’intensification différée se déroule en blocs qui durent généralement 8 semaines. Certains enfants dont le risque est élevé pourraient recevoir un bloc supplémentaire de chimiothérapie d’intensification différée selon leur propre plan de traitement. Elle peut être suivie d’un autre bloc de chimiothérapie d’entretien provisoire.»

Read more: http://www.cancer.ca/fr-ca/cancer-information/cancer-type/le...

Read more: http://www.cancer.ca/fr-ca/cancer-information/cancer-type/le...

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Note added at 13 heures (2018-03-07 15:29:45 GMT)
--------------------------------------------------

Here is the English version taken on the same site :'Delayed intensification is usually given 3–4 months after the child reaches remission from induction chemotherapy. It is given in blocks that usually last 8 weeks.

For some children at high risk, an extra block of delayed intensification chemotherapy may be given, depending on the child’s particular treatment plan. Delayed intensification

Read more: http://www.cancer.ca/en/cancer-information/cancer-type/leuke...

So my 'block' suggestion was indeed accurate.

https://www.google.ca/search?client=firefox-b&dcr=0&ei=xEafWoCGNobAjwSLyKSgDw&q=treatment+for+a+block+of+8+days+un+bloc+DEXAMETHASONE+20+g%2

Lorraine Dubuc
Canada
Local time: 04:20
Works in field
Native speaker of:

French

Notes to answerer

Asker: Hi Lorraine, thank you for your suggestion. I have added it to my glossary for Canadian English texts as it doesn't seem to be used much in the US which is currently my target audience. I finally went with cycle as "A cycle is the block of time in which a regimen is given" https://www.oncolink.org/cancer-treatment/chemotherapy/overview/chemotherapy-the-basics

Peer comments on this answer (and responses from the answerer)

neutral

Drmanu49: I don't think so Lorraine I believe it is related to the drug's potency.

13 mins

-> I thought it was the treatment itself and how it is administered, according to the sentence provided. I added a note with a reference. Please see reference above. I got the English version and 'block' is used.

agree

Herbmione Granger: This makes sense, especially since it's followed by (a round of) chemo. Not sure what the usual term in EN is or if you need one here.

6 hrs

disagree

liz askew: see my references

7 hrs

-> Has nothing to do with what is being discussed here, I think. You referred to nerve injections. This is about a treatment here I think. I found a reference in English and 'block' is indeed the right term. See references.

Reference comments

7 hrs peer agreement (net): -1

Reference: nerve block or nerve blockade

Reference information:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752844/
1.
Translate this page
by J Koné - ‎2015 - ‎Related articles
Le rôle des adjuvants associés aux anesthésiques locaux est démontré dans la qualité des blocs, toutefois leur innocuité reste à évaluer [18]. La dexaméthasone utilisée comme adjuvant chez notre patiente, a fait l'objet de nombreuses études avec une prolongation significative de la durée du blocanesthésique [8].

Local anesthetic nerve block (local anesthetic regional nerveblockade, or often simply nerve block) is a short-term nerve block involving the injection of local anesthetic as close to thenerve as possible for pain relief. ... The block provides pain relief during and after the surgery.

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Note added at 7 hrs (2018-03-07 09:04:02 GMT)
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https://www.evidence.nhs.uk/bnf/Search?pa=6&ps=50&q=dexameth...
Results 251 - 300 of 2030 - Plitidepsin (Aplidin) in combination with dexamethasone for multiple myeloma – third line June 2013. More: Horizon .... Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks: A Meta-analysis of Randomized Controlled Trials. Source: ...

liz askew
United Kingdom
Specializes in field
Native speaker of:

English
PRO pts in category: 3189

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