glomérules sclérosés en pain à cacheter

12:59 May 22, 2018 

Hi Anne, he has systemic lupus with skin and joint manifestations. Diagnosis hypothesis is lupus nephritis

12:57 May 22, 2018 

Thanks Liz for the additional sources. Very helpful!

08:27 May 22, 2018 

What is the patient's diagnosis/underlying disease? Based on the typical type of glomerular sclerosis occurring with this condition, it might be easier to find the typical English way to characterize this appearance.

06:30 May 22, 2018 

@Joanna I do feel the number of hits is not everything. Pain à cacheter may refer to a specific condition but it Is a descriptive term not a technical term.

17:10 May 21, 2018 

n the mesangial stalks of all glomeruli.
2) Focal glomerular obsolescence (FGO.). The coexistence
of optically normal glomeruli and sclerosed
glomeruli is characteristic of this type of lesion. The
affected glomeruli are shrunk into small wafer-like
formations of low cellularity that are positive for collagen
stains, and irregularly disseminated over the
renal parenchyma. Only those cases should be considered
as significant in which at least 15 to 20% of
glomeruli are sclerosed, and in which the sclerosis is
associated with conspicuous interstitial and tubular
damage. The great difficulty in children is to differentiate
such atrophic glomeruli from 'congenital glomerulosclerosis,'
a developmental anomaly which is frequently
found in the kidneys of infants and young children.
In congenital glomerulosclerosis, as described by
several authors [18, 19], there is neither accompanying
tubular atrophy nor interstitial fibrosis.
Several glomerular diseases, such as endo and extracapillary
glomerulonephritis or thrombotic microangiopathy
may lead to focal glomerular obsolescence
but when this histological picture is associated with a
nephrotic syndrome, it should again be considered as
an

17:06 May 21, 2018 

Thanks Liz I found that ref.

16:59 May 21, 2018 

www.kidney-international.org/article/S0085-2538(15)31256-4/pdf
by R Habib - ‎1973 - ‎Cited by 269 - ‎Related articles
terms focal glomerular sclerosis (FGS) or focal scler- .... affected glomeruli are shrunk into small wafer-like .... statistical appearances of hypertension and renal.