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PDE IV-Hemmer

English translation: Phsphodiesterase IV inhibitor

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GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
German term or phrase:PDE IV Hemmer
English translation:Phsphodiesterase IV inhibitor
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13:08 Aug 13, 2001
German to English translations [Non-PRO]
Medical
German term or phrase: PDE IV-Hemmer
used for the indication of asthma
caitriona
PDE IV inhibitor or Phosphodiesterase IV Inhibitor
Explanation:
See some references:

Bayer's Phosphodiesterase IV inhibitor has been undergoing clinical testing
since 1999 - in both patients with asthma and with chronic bronchitis. ...
www.webhealthplus.com/news/archives/reports/150700asthmacur...

Chiroscience Announces PDE IV Progress and R&D updates
Phase I study will assess the safety, tolerability and effects on key asthma inflammatory mediators of D4418, an oral PDE IV inhibitor
Research updates to be held 30 May and 2 June; AGM to be held 4 June
Chiroscience Group plc today announces the initiation of a Phase I study on D4418, an oral phosphodiesterase (PDE) type IV inhibitor being developed to treat asthma. This double blind, placebo controlled study in healthy male volunteers will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of D4418 following administration of ascending single oral doses. In addition, the study will investigate the effects of D4418 on plasma levels of key asthma inflammatory mediators.
www.medeva.co.uk/company_information/press_releases/chirosc... pr970513.html

Phosphodiesterase IV Inhibitors as Therapy for Eosinophil- ...
... drugs is the cyclic AMP-specific phosphodiesterase (PDE) or PDE IV. This isozyme ... examine the effect of the PDE IV inhibitor, R-rolipram, on three key ...
ehpnet1.niehs.nih.gov/docs/1994/Suppl-10/torphy.html

... Inhibitory Effect of a Novel Phosphodiesterase IV Inhibitor, T-440, on Antigen- and Chemical Mediator-Induced Bronchoconstrictions in Guinea Pigs In Vivo. ...
wwwsoc.nii.ac.jp/tjps/kyoto/jjp/TOC96-72(1)/96-72-001.html

HTH
Selected response from:

Ulrike Lieder
Local time: 08:33
Grading comment
4 KudoZ points were awarded for this answer

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Summary of answers provided
na +1PDE IV inhibitor or Phosphodiesterase IV InhibitorUlrike Lieder


  

Answers


23 mins peer agreement (net): +1
PDE IV inhibitor or Phosphodiesterase IV Inhibitor


Explanation:
See some references:

Bayer's Phosphodiesterase IV inhibitor has been undergoing clinical testing
since 1999 - in both patients with asthma and with chronic bronchitis. ...
www.webhealthplus.com/news/archives/reports/150700asthmacur...

Chiroscience Announces PDE IV Progress and R&D updates
Phase I study will assess the safety, tolerability and effects on key asthma inflammatory mediators of D4418, an oral PDE IV inhibitor
Research updates to be held 30 May and 2 June; AGM to be held 4 June
Chiroscience Group plc today announces the initiation of a Phase I study on D4418, an oral phosphodiesterase (PDE) type IV inhibitor being developed to treat asthma. This double blind, placebo controlled study in healthy male volunteers will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of D4418 following administration of ascending single oral doses. In addition, the study will investigate the effects of D4418 on plasma levels of key asthma inflammatory mediators.
www.medeva.co.uk/company_information/press_releases/chirosc... pr970513.html

Phosphodiesterase IV Inhibitors as Therapy for Eosinophil- ...
... drugs is the cyclic AMP-specific phosphodiesterase (PDE) or PDE IV. This isozyme ... examine the effect of the PDE IV inhibitor, R-rolipram, on three key ...
ehpnet1.niehs.nih.gov/docs/1994/Suppl-10/torphy.html

... Inhibitory Effect of a Novel Phosphodiesterase IV Inhibitor, T-440, on Antigen- and Chemical Mediator-Induced Bronchoconstrictions in Guinea Pigs In Vivo. ...
wwwsoc.nii.ac.jp/tjps/kyoto/jjp/TOC96-72(1)/96-72-001.html

HTH

Ulrike Lieder
Local time: 08:33
Native speaker of: German
PRO pts in pair: 3525

Peer comments on this answer (and responses from the answerer)
agree  Sven Petersson
6 mins
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