disreattività nervosa

Italian term or phrase:disreattività nervosa
English translation:dysponesis
Entered by: Joseph Tein

02:16 Dec 4, 2016
This question was closed without grading. Reason: Other

Italian to English translations [PRO]
Medical - Medical (general) / pharmacovigilance - adverse drug reactions - MedDRA terms
Italian term or phrase: disreattività nervosa
This is in a list of adverse reactions found in a report to the AIFA [Agenzia Italiana del Farmaco]. The form lists several of these along with their MedDRA [Medical Dictionary for Regulatory Activities] numbers:

10039906 - Crisi convulsiva
10042364 - Emorragia subdurale
10061428 - Appetito ridotto
10065699 - Stato di *disreattività nervosa*

This appears to be a very specialized, uncommon expression.

When I look through the few online sites that contain it, I find that some of them show "dysponesis" as the English equivalent. An online definition of dysponesis says: "Dysponesis (Dys - bad, faulty, or wrong; ponesis = effort, work or toil) is considered faulty, ineffectual, or misdirected expenditure of energy, or effort, that is characterized in “functional disorders”; that is, errors in neurophysiological signaling with the absence of related structural pathology."

It all seems very vague and non-specific. Is anyone familiar with this term? Can you explain it and suggest an appropriate English translation of "disreattività nervosa" or do I just need to trust that "dysponesis" covers it?

Thanks for your help.

(Further information on MedDRA from Wikipedia: " ... the adverse event classification dictionary endorsed by the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH).")
Joseph Tein
United States
Local time: 06:49

Discussion entries: 4


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