Glossary entry

Portuguese term or phrase:

método da cesta ou pá

English translation:

basket and paddle methods

Jun 4, 2002 06:29
22 yrs ago
Portuguese term

método da cesta ou pá

Portuguese to English Medical Medical: Pharmaceuticals Pharma
Os ensaios de dissolução devem ser realizados em condições tais como: método da cesta a 50/100 rpm ou pá 50/75/100 rpm.
Proposed translations (English)
4 +3 Basket and paddle methods

Proposed translations

+3
39 mins
Selected

Basket and paddle methods

Ver the following web site for the explanation:
http://216.239.35.100/search?q=cache:FS5pBLaXuWkC:www.dissol...

Different rotation speeds are specified in the various Pharmacopoieas and Guidances. For basket / paddle 50 - 100 (150) rpm are described in the FIP guidelines (16) and the European Pharmacopeia (19), whereas 100 rpm for basket and 50 - 75 rpm for paddle are recommended by the FDA (18). A final scientific decision regarding the velocity of rotation neither exists nor is to be expected other than on a product-by-product basis.

Peer comment(s):

agree Ligia Dias Costa
1 hr
agree Kathleen Goldsmith-Killing
5 hrs
agree rhandler
6 hrs
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4 KudoZ points awarded for this answer. Comment: "Thank you very much. It was of great help!!"
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