Glossary entry (derived from question below)
Portuguese term or phrase:
método da cesta ou pá
English translation:
basket and paddle methods
Jun 4, 2002 06:29
22 yrs ago
Portuguese term
método da cesta ou pá
Portuguese to English
Medical
Medical: Pharmaceuticals
Pharma
Os ensaios de dissolução devem ser realizados em condições tais como: método da cesta a 50/100 rpm ou pá 50/75/100 rpm.
Proposed translations
(English)
4 +3 | Basket and paddle methods | António Ribeiro |
Proposed translations
+3
39 mins
Selected
Basket and paddle methods
Ver the following web site for the explanation:
http://216.239.35.100/search?q=cache:FS5pBLaXuWkC:www.dissol...
Different rotation speeds are specified in the various Pharmacopoieas and Guidances. For basket / paddle 50 - 100 (150) rpm are described in the FIP guidelines (16) and the European Pharmacopeia (19), whereas 100 rpm for basket and 50 - 75 rpm for paddle are recommended by the FDA (18). A final scientific decision regarding the velocity of rotation neither exists nor is to be expected other than on a product-by-product basis.
http://216.239.35.100/search?q=cache:FS5pBLaXuWkC:www.dissol...
Different rotation speeds are specified in the various Pharmacopoieas and Guidances. For basket / paddle 50 - 100 (150) rpm are described in the FIP guidelines (16) and the European Pharmacopeia (19), whereas 100 rpm for basket and 50 - 75 rpm for paddle are recommended by the FDA (18). A final scientific decision regarding the velocity of rotation neither exists nor is to be expected other than on a product-by-product basis.
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