10ТД

English translation: 10 therapeutic doses

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Russian term or phrase:10ТД
English translation:10 therapeutic doses

14:28 Feb 14, 2014
    The asker opted for community grading. The question was closed on 2014-02-17 15:54:11 based on peer agreement (or, if there were too few peer comments, asker preference.)


Russian to English translations [PRO]
Medical - Biology (-tech,-chem,micro-)
Russian term or phrase: 10ТД
I'm translating a text on lab research. The phrase is as follows:
вводили ... при помощи зонда в дозах 30 мг/кг (10ТД) и 300 мг/кг (100ТД).

What is "10ТД" in this context?

Many thanks,

Julia
Julia Zarubinska-Toepritz
United Kingdom
Local time: 03:39
10 therapeutic doses
Explanation:
Please see the reference information below.

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Note added at 31 mins (2014-02-14 15:00:20 GMT)
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LDN fills all the requirements for safety and efficacy in ameliorating a large proportion of auto immune disease.

*******It has been tested at doses 10 times therapeutic dose and found safe.******* It has been in field use for more than 25 years. There are clinical studies, double blind placebo, in Crohn's Disease and Fibromyalgia documenting efficacy in diseases thought to have auto immune mechanisms.

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Note added at 36 mins (2014-02-14 15:04:49 GMT)
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"Therapeutic doses of theophylline exert proconvulsant effects in developing mice."
Authors: Yokoyama H, Onodera K, Yagi T, Iinuma K.
Brain & development, September 1997, vol./is. 19/6(403-7), 0387-7604.
(available as free previews)

"We studied the effect of therapeutic doses of theophylline on electrically-induced convulsions in developing mice... ..."

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Note added at 39 mins (2014-02-14 15:08:44 GMT)
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Lippincott's Manual of Toxicology
http://books.google.com.ua/books/about/Lippincott_s_Manual_o...

Activated charcoal should be considered in all patients with recent intentional overdose of more than *******10 therapeutic doses*******

Etc., etc.
Selected response from:

Oleksandr Kupriyanchuk
Ukraine
Local time: 05:39
Grading comment
Thank you.
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +310 therapeutic doses
Oleksandr Kupriyanchuk
Summary of reference entries provided
ТД = терапевтическая доза
Oleksandr Kupriyanchuk

  

Answers


27 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
10 ТД
10 therapeutic doses


Explanation:
Please see the reference information below.

--------------------------------------------------
Note added at 31 mins (2014-02-14 15:00:20 GMT)
--------------------------------------------------

LDN fills all the requirements for safety and efficacy in ameliorating a large proportion of auto immune disease.

*******It has been tested at doses 10 times therapeutic dose and found safe.******* It has been in field use for more than 25 years. There are clinical studies, double blind placebo, in Crohn's Disease and Fibromyalgia documenting efficacy in diseases thought to have auto immune mechanisms.

--------------------------------------------------
Note added at 36 mins (2014-02-14 15:04:49 GMT)
--------------------------------------------------

"Therapeutic doses of theophylline exert proconvulsant effects in developing mice."
Authors: Yokoyama H, Onodera K, Yagi T, Iinuma K.
Brain & development, September 1997, vol./is. 19/6(403-7), 0387-7604.
(available as free previews)

"We studied the effect of therapeutic doses of theophylline on electrically-induced convulsions in developing mice... ..."

--------------------------------------------------
Note added at 39 mins (2014-02-14 15:08:44 GMT)
--------------------------------------------------

Lippincott's Manual of Toxicology
http://books.google.com.ua/books/about/Lippincott_s_Manual_o...

Activated charcoal should be considered in all patients with recent intentional overdose of more than *******10 therapeutic doses*******

Etc., etc.

Oleksandr Kupriyanchuk
Ukraine
Local time: 05:39
Works in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 4
Grading comment
Thank you.

Peer comments on this answer (and responses from the answerer)
agree  Naveen Kar
27 mins

agree  Natalia Avseenko
2 hrs

agree  cyhul
11 hrs
Login to enter a peer comment (or grade)




Reference comments


21 mins peer agreement (net): +1
Reference: ТД = терапевтическая доза

Reference information:
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...

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Note added at 22 mins (2014-02-14 14:50:50 GMT)
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"ТД – терапевтическая доза
...
Изучили мутагенное действие фармакологической субстанции киллевир-16 методом учета хромосомных аберраций в клетках костного мозга мышей C57Bl/6 при четырехкратном пероральном введении в эквитерапевтической дозе (1 ТД) и десятикратно её превышающей (10 ТД). Дозы для животных рассчитаны по соотношению площади поверхности тела человека и мыши: терапевтическая доза для человека – 40 мг, для мыши 1 ТД=0,13 мг на особь, 10 ТД=1,33 мг на особь. Каждая экспериментальная группа представлена пятью самцами и пятью самками."

Oleksandr Kupriyanchuk
Ukraine
Works in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 4

Peer comments on this reference comment (and responses from the reference poster)
agree  Natalia Volkova
2 mins
Login to enter a peer comment (or grade)



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