кожно-резорбтивное действие

08:08 Mar 16, 2018
Russian to English translations [PRO]
Law/Patents - Medical: Pharmaceuticals / Композиции для регулирования полового поведения животных
Russian term or phrase: кожно-резорбтивное действие
(Исследование кожно-резорбтивного действия предлагаемого препарата)
Материалы и методы:
Изучение кожно-резорбтивного действия препарата, приготовленного по примеру 18, изучалось в однократном и повторном (5 дней) опытах на белых крысах-самцах массой 180-200 г. Для исследования были отобраны клинически здоровые особи без видимых повреждений кожного покрова. Животные были разделены на три группы:
1 группа - контроль (10 животных).
2 группа - однократная обработка (10 животных).
3 группа - пятикратная обработка (10 животных).
Целью однократного опыта являлось определение смертельных доз и соответственно определение кожно-орального коэффициента (К к/о):
ЛД50кожа
К к/о= ;
ЛД50желудок.

Я так понимаю, что подразумевается Dermal toxicity testing?
Описан вот здесь - http://alttox.org/mapp/toxicity-endpoints-tests/dermal-penet...

Спасибо!
Wolfskin
Local time: 16:47


Summary of answers provided
4 +1skin-resorptive effect
Alieksei Seniukovich
4Dermal Absorption (and Toxicity) Assessment (testing)/ percutaneous absorption Assessment (testing)
Turdimurod Rakhmanov
3skin-resorptive effect
Vladyslav Golovaty


  

Answers


1 min   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
skin-resorptive effect


Explanation:
!

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Note added at 2 mins (2018-03-16 08:10:52 GMT)
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Это буквальный перевод вашего термина.
Dermal toxicity testing имеет более широкое значение.

Alieksei Seniukovich
Belarus
Local time: 16:47
Specializes in field
Native speaker of: Native in RussianRussian
PRO pts in category: 43

Peer comments on this answer (and responses from the answerer)
agree  Natalie
11 days
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2 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
skin-resorptive effect


Explanation:
Study of skin-resorptive effect of the proposed drug

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Note added at 5 mins (2018-03-16 08:14:23 GMT)
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"Orgsept" on the indicators of acute toxicity and its harmful effects on laboratory animals. The determination of acute toxicity, the study of the cumulative and skin-resorptive action of the drug "Orgasept" was performed on clinically healthy white mice, and the irritating effect and sensitizing properties were ...
ojs.mdpu.org.ua/index.php/biol/article/download/_.../2660

Vladyslav Golovaty
Ukraine
Local time: 16:47
Works in field
Native speaker of: Native in RussianRussian
PRO pts in category: 90
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45 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
Dermal Absorption (and Toxicity) Assessment (testing)/ percutaneous absorption Assessment (testing)


Explanation:
Dermal Absorption (and Toxicity) Assessment (testing)/ percutaneous absorption Assessment (testing)


    https://www.researchgate.net/publication/235332402_Animal_Skin_Morphology_and_Dermal_Absorption
Turdimurod Rakhmanov
Kyrgyzstan
Local time: 19:47
Specializes in field
Native speaker of: Native in UzbekUzbek, Native in KirghizKirghiz
PRO pts in category: 20
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