ruido supraespinal

13:04 May 8, 2018
Spanish to English translations [PRO]
Medical - Medical: Health Care / Orthopedics - neck pain
Spanish term or phrase: ruido supraespinal
En procesos de sensibilización central estímulos cutáneos podrían activar mecanismos de nocicepción.
Este aspecto, sumado a una reducción de los umbrales de dolor, podría generar un ruido supraespinal por una pérdida de inhibición repercutiendo en una alteración de la precisión espacial táctil, siendo esta hipótesis reforzada por evidencia que sugiere que la TPD depende en mayor medida de la magnitud del estimulo que de su dimensión espacial.

Not finding much on "supraspinal noise", although the idea works - thoughts?

TIA, Juliette
ServingMed.com
Netherlands
Local time: 06:54


Summary of answers provided
4supraspinal noise
George Simon
Summary of reference entries provided
supraspinal mechanism / component
Neil Ashby

Discussion entries: 2





  

Answers


6 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
supraspinal noise


Explanation:
Neil's comment is partially correct but it generalizes: see below

It seems unlikely that transmission of the stimuli to
the brain is reduced in people with back pain because of the S1
response evoked by electrical cutaneous stimulation at the
back is not delayed, nor diminished, in patients with back
pain. 6 Perceptual threshold is also unaffected. 10 However,
spinal mechanisms mediate central sensitisation, via which
peripheral Aβ cutaneous input activates spinal nociceptors.
18 Therefore, although the speed and magnitude of the
cortical response to cutaneous stimulation is unaffected, the
spinally evoked noxious input may lead to supraspinal noise
and a loss of normal inhibition. Whether spinal sensitisation
contributes or not, supraspinal mechanisms seem most
likely to explain the loss of tactile acuity in back pain
from: Tactile acuity and lumbopelvic motor control in
patients with back pain and healthy controls

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Note added at 22 hrs (2018-05-09 11:25:15 GMT)
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Hello Neil,
Thanks very much for your reply, although I must disagree with your reasoning (I think it goes off the tangent to invoke the origin of both the writer and translator) and in defense of my position regarding the original article brought forth by Servingmed (in Spanish) the original writer clearly states: 1. Estímulos cutáneos podrían activar mecanimo de nocicepción 2.Mecanismos de nocicepción + disminución del umbral del dolor=> pérdida de inhibición(supraespinal)=generación de ruido supraespinal=>alteración de la precisión espacial táctil. The word ruido here is employed, borrowed from the world of radio communications because this particular case deals with electrical conduction pathways within the nervous system ( both CNS and SNS), and it implies that said noise alters the expected results even though it is a consequence of or originates in a supraspinal (as in CNS) mechanism.With regards to the cited article, it coincides perfectly with the original article and bolsters the above stated opinion from a scientific point of view.


    Reference: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.845...
George Simon
Venezuela
Local time: 05:54
Works in field
Native speaker of: Native in SpanishSpanish, Native in EnglishEnglish
PRO pts in category: 12

Peer comments on this answer (and responses from the answerer)
neutral  Neil Ashby: "supraspinal noise" gets 4 hits (probably in translations - the text in your reference looks to be a non-native author, e.g. "not delayed, nor diminished"), "supraspinal mechanism" 5,379
13 hrs
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Reference comments


1 hr
Reference: supraspinal mechanism / component

Reference information:
Evidence for a supraspinal mechanism in the opioid-mediated antinociceptive effect of ketamine.
https://www.ncbi.nlm.nih.gov/pubmed/1814555

Buprenorphine has an opioid component to its supraspinal mechanism of analgesic action. Our present results reveal an additional supraspinal component insensitive to naloxone, PTX and nociceptin/orphanin-FQ, but involving Gz protein and Ser/Thr protein phosphatase.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721267/

Not sure if these findings are relevant, just pointers, sorry no time to delve further.

Neil Ashby
Spain
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 52
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