Glossary entry (derived from question below)
Spanish term or phrase:
procedimiento de estadiaje único de Fleming
English translation:
Fleming's single-stage procedure
Nov 5, 2003 13:00
21 yrs ago
1 viewer *
Spanish term
procedimiento de estaadiaje único de Fleming
Spanish to English
Medical
clinical trial protocol, drug therapy
Siguiendo el ‘procedimiento de estadiaje único de Fleming’ el 20% se considera la mínima tasa de respuesta aceptada en esta población y la tasa de respuesta óptima con STI 571 en monoterapia.
Proposed translations
(English)
4 +2 | Fleming's [standard] single-stage test procedure | Elena Sgarbo (X) |
4 | Fleming's one-sample multiple testing procedure | Parrot |
Proposed translations
+2
48 mins
Selected
Fleming's [standard] single-stage test procedure
Parrot is on the right track with her response, but I believe the text refers only to a part of the "one-sample multiple testing procedure". That part is the last one of the multiple testing , i.e., the last test, called "single stage".
Good luck
Elena
One-sample multiple testing procedure for phase II clinical trials. Fleming TR.
Commonly, the central objective of Phase II clinical trials is the assessment of the antitumor 'therapeutic efficacy' of a specific treatment regimen. It is of interest to formulate test procedures which can be employed in these trials to decide whether or not this therapeutic efficacy warrants further investigation. For ethical reasons, these procedures should allow for early termination if initial results are extreme. In this paper, a one-sample multiple testing procedure is proposed which employs the **standard single-stage test procedure** at the last test, and which both allows for early termination and essentially preserves the size, power and simplicity of the **single-stage procedure**.
Good luck
Elena
One-sample multiple testing procedure for phase II clinical trials. Fleming TR.
Commonly, the central objective of Phase II clinical trials is the assessment of the antitumor 'therapeutic efficacy' of a specific treatment regimen. It is of interest to formulate test procedures which can be employed in these trials to decide whether or not this therapeutic efficacy warrants further investigation. For ethical reasons, these procedures should allow for early termination if initial results are extreme. In this paper, a one-sample multiple testing procedure is proposed which employs the **standard single-stage test procedure** at the last test, and which both allows for early termination and essentially preserves the size, power and simplicity of the **single-stage procedure**.
4 KudoZ points awarded for this answer.
Comment: "Thanks Elena and Parrot, I went back and checked the context in the document, it seems to be a reference only to the single-stage part of the procedure.
Jill"
10 mins
Spanish term (edited):
procedimiento de estaadiaje �nico de Fleming
Fleming's one-sample multiple testing procedure
See if this is the one (Phase II Trials).
--------------------------------------------------
Note added at 27 mins (2003-11-05 13:27:45 GMT)
--------------------------------------------------
The Mayo Clinic has the bibliography (NIH abstract files open very slowly):
http://www.mayo.edu/hsr/techrpt.html
--------------------------------------------------
Note added at 27 mins (2003-11-05 13:27:45 GMT)
--------------------------------------------------
The Mayo Clinic has the bibliography (NIH abstract files open very slowly):
http://www.mayo.edu/hsr/techrpt.html
Reference:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=7082756
Something went wrong...