engrosamiento de aspecto binucleado

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12:25 May 28, 2018
Spanish to English translations [PRO]
Medical - Medical: Health Care / Oral health - Geographic tongue
Spanish term or phrase: engrosamiento de aspecto binucleado
Características citológicas e histológicas
Las particularidades citológicas de la LG fueron descritas por Scariot et al,21 quienes especificaron un grado II de Papanicolau, es decir un frotis normal con cambios inflamatorios.
Distinguieron el aumento del tamaño nuclear, incrementándose así su relación con respecto al citoplasma.
Los núcleos presentaban un halo perinuclear debido a su engrosamiento de aspecto binucleado.

"engrosamiento de aspecto binucleado" doesn't make much sense. Growth/thickening towards binuclearity? At the moment I have "of binuclear appearance" but that doesn't seem quite right either.

Thoughts?
ServingMed.com
Netherlands
Local time: 01:23

Summary of reference entries provided
This might help
Helena Chavarria
see
liz askew

  

Reference comments


1 hr
Reference: This might help

Reference information:
A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus.

Koilocytosis
Koilocytosis or koilocytic atypia or koilocytotic atypia are terms used in histology and cytology to describe the presence of koilocytes in a specimen.[1]

Koilocytes may have the following cellular changes:

Nuclear enlargement (two to three times normal size).
Irregularity of the nuclear membrane contour
A darker than normal staining pattern in the nucleus, known as Hyperchromasia.
A clear area around the nucleus, known as a perinuclear halo.

https://en.wikipedia.org/wiki/Koilocyte

Binucleated cells are cells that contain two nuclei. This type of cell is most commonly found in cancer cells and may arise from a variety of causes. Binucleation can be easily visualized through staining and microscopy. In general, binucleation has negative effects on cell viability and subsequent mitosis.

They also occur physiologically in hepatocytes, chondrocytes and in fungi (dikaryon).

https://en.wikipedia.org/wiki/Binucleated_cell

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Note added at 1 hr (2018-05-28 14:09:57 GMT)
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1. Koilocytic cytoplasmic vacuolisation: perinuclear haloes surrounding cell nuclei.
2. Koilocytic nuclear change: pyknosis – nuclear material that may be irregular in size, shape and staining properties. The nucleus is frequently acentric. Binucleation may be apparent.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768439/

engrosamiento = enlargement
de aspecto binucleado = apparent binucleation

Helena Chavarria
Spain
Works in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 40
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3 hrs
Reference: see

Reference information:
Diagnostic Cytopathology - Page 587 - Google Books Result
https://books.google.co.uk/books?isbn=0702031542
Winifred Gray, ‎Gabrijela Kocjan - 2010 - ‎Medical
Note how some cells are bi-nucleate. cytoplasmic rim. The shape of the clear ... the cytoplasm or the small neat area of pallor seen in perinuclear halo formation.
Clinical Gynaecology - Page 473 - Google Books Result
https://books.google.co.uk/books?isbn=0702173053
T. F. Kruger, ‎M. H. Botha - 2007 - ‎Medical
Round or oval cell with increased relative nuclear area. ... Note nuclear hyperchromasia and crisp condensed cytoplasm around cell walls with resulting clear perinuclear halo. ... The nucleus may be single or binucleate and slightly enlarged.

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 609
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