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08:55 Nov 5, 2001 |
Spanish to English translations [PRO] Science | |||||||
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| Selected response from: MJ Barber Spain Local time: 18:27 | ||||||
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5 +2 | Erythropoietin |
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4 | ver ref. |
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4 | ver ref. |
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4 | erythropoietine |
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4 | Erythropoietin |
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Erythropoietin Explanation: both also shortened to EPO Mosby Medical Dictionary Erythropoietin, (EPO), a glycoprotein hormone produced primarily by cells of the peritubular capillary endothelium of the kidney, is responsible for the regulation of red blood cell production. Secondary amounts of the hormone are synthesized in liver hepatocytes of healthy adults. In premature as well as full term infants, the liver is the primary site of EPO production. The kidney becomes the primary site of EPO synthesis shortly after birth. EPO production is stimulated by reduced oxygen content in the renal arterial circulation. Circulating EPO binds to EPO receptors on the surface of erythroid progenitors resulting in replication and maturation to functional erythrocytes by an incompletely understood mechanism. Reference: http://path.upmc.edu/consult/rla/july1995.html |
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