|English to Chinese: 沙门氏菌疫苗M735|
General field: Science
|Source text - English|
The aim of the study was to test for the protection conferred by two formulations of the Salmonella vaccine M735 against an oral Salmonella Enteritidis (SE) challenge in laying hens at the end of the laying period (52 weeks age). The efficacy was assessed through fecal re-excretion of the challenge strain.
During their initial rearing period, the birds received a standard vaccination programme, as would be used in the field. In addition, 2 groups of pullets were immunised by intramuscular injections of M735 vaccine at 6 and 16 weeks of age. At D0 of the study, when they were 52 weeks of age, the hens were challenged by crop-gavage with ca.8 log10 colony forming units (CFU) per bird of SE16530, a nalidixate-resistant derivative of a PT4 field isolate. The SE serology status of each bird was checked before the challenge.
|Translation - Chinese|
|Chinese to English: 子宫肌瘤III期多中心随机对照临床试验|
General field: Medical
|Source text - Chinese|
|Translation - English|
The efficacy of Leuprorelin Acetate in treating uterine leiomyomas was assessed by conducting two independent, phase III, randomized and multicentre controlled clinical trials in uterine leiomyomas patients during a 3-month (84-day) period. Clinical trial 1 was a randomized, positive drug control, multicentre trial. The uterine leiomyomas patients received the positive control drug Leuprorelin Acetate subcutaneously (q28 d). Clinical trial 2 was a randomized, double-blind, placebo-controlled, multicentre trial. The main therapeutic effect index was the maximum reduction rate in fibroid volume after drug administration. The secondary therapeutic effect indexes were alleviation of anemia after drug administration including changes of RBC count, hemoglobin concentration and hematocrit, as well as alleviation of clinical symptoms including changes of menstrual blood volume, pressure and abdominal pain during and in between menstrual periods.