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English to Italian: Mushrooms and Cardiovascular diseases General field: Medical Detailed field: Medical: Cardiology
Source text - English Nowadays, cardiovascular diseases are a major cause of
death across many industrialized countries. Thus, Mensink et
al. have emphasized that cardiovascular diseases have a
multifactorial aetiology being mainly caused by atherosclerosis,
and have identified potential risk biomarkers such as
lipid and lipoprotein metabolism, haemostatic function,
oxidative damage, homocysteine metabolism, and blood
pressure. The hypocholesterolemic action of edible mushrooms
has been reported, by Kaneda and
Tokuda, who studied cholesterol lowering properties of
Lentinus edodes, Auricularria polytricha, Flammulina velutipes
and Agaricus bisporus. Additionally investigations from Bobek
and coworkers were focused on the hypocholesterolemic
effects of Pleurotus ostreatus, which revealed a lipid
peroxidation inhibition and a suppression of the activity of
HMG-CoA reductase in both normocholestolemic and hypercholesterolemic
animal models. Indeed, some competitive
inhibitors of HMG-CoA reductase have been isolated from
different mushrooms such as eritadenine from L. edodes and meviolin from Pleurotus sp. Besides, some mushrooms
have shown hypotensive effect when blood pressure is
already high. On the other hand, the presence of
antioxidant and anti-inflammatory compounds
in mushrooms might be clinically relevant in the
management of heart and circulation health complications.
There are some mushroom components involved in cardiovascular
diseases prevention or treatment (proteins, lipids,
vitamins, fibers, phenolic compounds and minerals). However,
the implicated mechanisms are not yet completely
elucidated.
Translation - Italian Al giorno d’oggi, le malattie cardiovascolari rappresentano una delle maggiori cause di morte in molti paesi industrializzati. Mensik et al. hanno evidenziato che le malattie cardiovascolari presentano un'eziologia multifattoriale, causata principalmente dall’aterosclerosi, e hanno identificato dei potenziali biomarcatori di rischio, come il metabolismo dei lipidi e delle lipoproteine, la funzione emostatica, lo stress ossidativo, il metabolismo dell’omocisteina e la pressione sanguigna. L’azione ipocolesterolemica dei funghi commestibili è stata riportata da Kaneda e Tokuda in uno studio sulle proprietà relative all’abbassamento di colesterolo del Lentinus edodes, dell’Auricularria polytricha, della Flammulina velutipes e dell’Agaricus bisporus. Ulteriori indagini, condotte da Bobek e colleghi, incentrate sugli effetti ipocolesterolemici del Pleurotus ostreatus, hanno rivelato un’inibizione della perossidazione dei lipidi e la soppressione delle attività dell’HMG-CoA reduttasi in entrambi i modelli, animali normocolesterolemici e ipocolesterolemici. Infatti, sono stati isolati alcuni inibitori competitivi dell’HMG-CoA reduttasi da diversi funghi, come l’eritadenina dal L. edodes e il meviolin dal genere Pleurotus. Inoltre, alcuni funghi hanno mostrato effetti ipotensivi quando la pressione sanguigna è già elevata. D’altra parte, la presenza di composti antiossidanti e antinfiammatori nei funghi potrebbe essere clinicamente rilevante nella gestione di complicazioni della salute del cuore e della circolazione. Esistono alcune componenti coinvolte nella prevenzione e nel trattamento di malattie cardiovascolari (proteine, lipidi, vitamine, fibre, composti fenolici e minerali). Tuttavia, i meccanismi implicati non sono stati ancora chiariti del tutto.
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Years of experience: 16. Registered at ProZ.com: Jan 2018.
Born in Sicily to a bilingual family, my roots go deep into Greece where I spent most of my childhood. I grew up speaking Italian and Greek. My education comes from the Italian school and University, I got my bachelor’s degree in Business Administration while working as a teacher and translating. I have 5+ years technical translation experience in the medical/pharmaceutical industry. In addition, I provide exceptional translation services in other fields: e.g. marketing/business, tourism, etc. CV available upon request.
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