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English to Japanese: https://www.autonews.com/automakers-suppliers/uaw-president-takes-leave-absence-amid-corruption-probe General field: Tech/Engineering Detailed field: Automotive / Cars & Trucks
Source text - English Rory Gamble, vice president of the UAW-Ford department, will be acting president after Gary Jones requested a leave of absence, according to an email to union employees obtained by Automotive News.
DETROIT — UAW President Gary Jones is taking a leave of absence as prosecutors in a widening corruption probe appear to be closing in on possible charges against him.
Rory Gamble, the vice president in charge of the UAW's Ford Motor Co. department, will be acting president, the UAW said Saturday. Both changes are effective Sunday.
The union's International Executive Board held an emergency meeting earlier Saturday in which Jones asked for the leave of absence, according to an email from Jones to union employees that was obtained by Automotive News.
“The UAW is fighting tooth and nail to ensure our members have a brighter future. I do not want anything to distract from the mission," Jones said in a statement issued by the union. "I want to do what’s best for the members of this great union."
Jones has been implicated in the federal corruption investigation that so far has resulted in 12 charges and 10 guilty pleas. His decision to go on paid leave comes two days after prosecutors accused a former top aide to Jones and six other officials of embezzling $1.5 million in union funds and filing false expense reports to conceal the wrongdoing.
One of the alleged co-conspirators is identified in public documents only as "UAW Official A.” That person is Jones, The Detroit News has reported, citing sources familiar with the case. Jones has not been charged with any wrongdoing.
Jones did not attend Friday’s meeting of the UAW’s National Ford Council, according to a person with knowledge of the situation. The council voted to send a tentative labor agreement with Ford to rank-and-file members for ratification.
Jones was named the union’s president in June 2018. The News, citing a source, said Jones has agreed to repay any salary received while on paid leave if he is convicted of a crime in connection to the corruption probe.
Gamble, in a statement, said he will remain focused on the union’s ongoing contract negotiations with the Detroit 3.
“Together throughout the last few months, we’ve achieved substantial victories for UAW members and we know that we have more work to do,” he said. “We want better health care coverage, better salaries and respect for our work. That will not change.”
UAW ScandalUAW Scandal timeline and key figures: In charges filed since July 2017, federal prosecutors have revealed that millions of dollars intended to train workers was instead spent by some UAW leaders on assorted luxuries. The charges have exposed fraud within the massive U.S. auto manufacturing union. Will this scandal spread? HERE IS A TIMELINE AND OUR LIST OF KEY PLAYERS.
On Thursday, Edward Robinson, who was head of a UAW regional community action program council, was charged with conspiracy to embezzle union funds and conspiracy to defraud the U.S. Another one of Robinson’s accused co-conspirators, UAW Region 5 Director Vance Pearson, has been charged and was placed on leave from the union in early October.
The latest complaint includes a number of potentially incriminating details about UAW Official A.
According to the complaint, Official A told Robinson “in or about” late 2017 they needed to “halt the cash embezzlement portion of the conspiracy because of the ongoing federal criminal investigation of the United Auto Workers union and because of a new UAW position being taken by UAW Official A.”
Jones was named the union’s president in June 2018.
Official A also promised to “take care of” one of Robinson’s relatives with a “sham job” if Robinson agreed to take sole responsibility for a portion of the embezzlement, according to the complaint. It also said Official A told Robinson in May 2019 he wished they “burned the records” related to the embezzlement scheme.
The UAW’s Solidarity House headquarters has been shuttered since July due to a fire in the union's information technology department that also damaged adjacent public relations office space. Arson has been ruled out as a cause of the fire.
Pearson later told Robinson he’d get him a “burner phone” to avoid a federal wiretap, and that he should “get rid of” any incriminating evidence.
The complaint also notes that UAW Official A was in possession of more than $32,000 in cash at his personal residence on August 28. Jones’ home was raided that day, along with the homes of other UAW officials, and media reports quoted witnesses saying were investigators counting cash.
Japanese to English: Medicine/Pharmacology General field: Medical Detailed field: Medical: Pharmaceuticals
Source text - Japanese E. 医薬・薬理
試験では、主要器官の機能（中枢神経系、心血管系および呼吸器系）に対するABC-123の影響を調べた。In vivo 試験は、Sprague-Dawley系ラットおよびテレメトリー装置を装着したカニクイザルを用いて行った。テレメトリー装置で記録した無麻酔カニクイザルの心血管系パラメータを測定した。動物には臨床適用経路とされている皮下投与を適用した。カニクイザルでは、5日間の漸増投与により0.4 mg/kgが最大耐量であった。ECG波形の形態およびリズムには、ABC-123の0.4 mg/kg投与20時間後まで影響は認められなかった。心臓カリウムチャネルおよびhERGの阻害効果を測定した。ウサギプルキンエ線維での活動電位およびCHO細胞で起こるhERGカリウムイオンチャンネルからテール電流を用いてQT延長を評価した。この試験は、パッチクランプ法により、hERG cDNAを安定的に導入したHEK293細胞から得られるhERGテール電流に対するABC-123の影響を評価するために実施した。ABC-123の適用によってHERGテール電流は阻害されないと結論された。
Translation - English E. Medicine/Pharmacology
On this testing, an effect of ABC-123 on main organs (Central nervous, cardiovascular, and respiratory systems) was researched. In Vivo testing was done on sprague-dawley rats and long-tailed macaque equipped with telemetry device. Then the cardiovascular
parameters from the long-tailed macaque under non-anesthetic state was measured. Hypodermic injection was used on the animals as it is considered a clinical application path. As for the long-tailed macaque, the maximum tolerated dose was 0.4 mg/kg over 5 days via titration method. ECG waveform and rhythm remained unaffected until 20 hours after ABC-123 was administered at 0.4 mg/kg. The inhibitory effect on cardiovascular Potassium channel and hERG were measured. QT prolongation was
evaluated using tail current from Potassium ion channel initiated inside CHO cells, and action potential in Purkinje’s Fiber of a rabbit. This testing was performed to determine the effect of ABC-123 against hERG tail current retrieved from HEK 293 cells which stably introduced hERG cDNA via patch-clamp technique. It is concluded that HERG tail current would not be inhibited by applying ABC-123.
Japanese to English: Medicine/Clinical Trial General field: Medical
This clinical trial is intended for those who have had a radiation therapy or XXX treatment history, and is a first-time recurrent glioblastoma patient. This clinical trial consists of screening period, treatment period, and follow-up period. The patient has to meet all inclusion criteria, does not meet any of exclusion criteria, and has the approval of the principal investigator or sub investigator as the candidate for this trial. During treatment period, medication is administered on the first day of each cycle which is two weeks. The medication cycle can repeat as long as the examinee do not meet any criteria on administration discontinuation guideline or administration postponement guideline. If the examinee meets a criteria on administration discontinuation guideline, end-of-treatment evaluation (At time of discontinuation) is performed, and the patient will transition to follow-up period. The design overview of this clinical trial is illustrated in figure #2.
The inclusion criteria: A patient who are diagnosed histologically - by WHO classification - grade Ⅳ glioma (Both glioblastoma and glioma will be noted as glioma). A patient who has 12 weeks or more survival expectancy at time of obtaining informed consent. A patient of childbearing potential who agrees to use double contraception methods and not to breast-feed from the time of informed consent to after at least 320 days of the final medication administration.
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