English to Chinese: Head and Neck Cancer Recurrence General field: Medical Detailed field: Medical: Health Care
Source text - English Skinner explained that infection with certain types of HPV can cause some cases of HNSCC, but that many cases are HPV-negative. He noted that patients with HPV-negative HNSCC have particularly poor outcomes following treatment and that he and his colleagues focused this study on identifying and validating potentially targetable biomarkers to potentially improve survival in this group of patients.
Translation - Chinese Skinner解释到，某些头颈部鳞状细胞癌 (HNSCC) 病例是由于感染了特定类型的人乳头瘤病毒病毒 (HPV) 引起的，但是许多病例却是阴性的。他强调，HPV阴性头颈部鳞癌病人接受治疗后，结果特别不好。在这项研究中，他和他的同事着重于确定和验证潜在的可靶向生物标志物，用以提高这类病人的生存率。
Chinese to English: Fatty liver - 脂肪肝 General field: Medical Detailed field: Medical (general)
Source text - Chinese 本调查中脂肪肝组高脂血症、高血糖、高血压病、高尿酸血症的患病率均显著高于非脂肪肝组，提示本调查人群的脂肪肝与高血脂、高血糖、高血压、高尿酸关系密切。目前已确定的引起NAFLD的危险因素包括代谢综合征，糖尿病和肥胖。研究显示，2型糖尿病患者NAFLD患病率为40％~69.5％，肥胖人群中NAFLD患病率为57.4％~74%，高脂血症患者NAFLD患病率为27％～92％，Donati等研究发现非肥胖非糖尿病的高血压人群中NAFLD患病率是普通人群的2～3倍(30.9％vs12.7％)。而脂肪肝中合并血脂紊乱的患者高达50%，其中以血浆TG升高为主。血浆TG的升高为心血管疾病发病的重要危险因素，有证据显示NAFLD与心血管疾病的发生率密切相关，其中动脉硬化性心血管疾病、肝硬化是NAFLD患者常见的死亡原因。因此，我们不仅应该把中心性肥胖、2型糖尿病、血脂紊乱和高血压看作是NAFLD的危险因素及临床诊断，更应重视它们作为心血管、肾脏和肝脏等疾病进一步发展及恶化的高危因素。所以，对NAFLD临床治疗的关键是减少以上危险因素，并且应该应用现有知识对普通人群实施预防为主的策略。
Translation - English In this study, the prevalence of hyperlipidemia, hyperglycemia, hypertension, and hyperuricemia was significantly higher in the fatty liver group than in the non-fatty liver group, suggesting a strong association between fatty liver and those diseases in our study population. At present, identified risk factors of NAFLD include metabolic syndrome, diabetes, and obesity. The reported prevalence of NAFLD in patients with type II diabetes varied between 40% and 69.5%, in patients with obesity varied between 57.4% and 74%, and in patients with hyperlipidemia varied between 27% and 92%. Donati et al. found the prevalence of NAFLD, as compared with the general population, was 2-3 times as high among hypertension patients without obesity and diabetes (30.9％vs12.7％). The dyslipidemia rate in individuals with a fatty liver is up to 50%, and the majority is plasma TG elevation, which is an important risk factor for cardiovascular disease. There is evidence that NAFLD is closely related to the incidence of cardiovascular diseases, and arteriosclerotic cardiovascular disease and cirrhosis are common causes of death in NAFLD patients. Thence, we should not only consider central obesity, type 2 diabetes, dyslipidemia, and hypertension as risk factors and clinical diagnostic criteria for NAFLD but also appreciate them as high-risk factors for progression of cardiovascular, kidney and liver diseases. Therefore, the key point to treat NAFLD is to reduce those risk factors, and disease prevention among the general population based on existing knowledge should be the main strategy.
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I have a strong background in biochemistry and nutrition. I have more than 7 years research experience in the healthcare area, focusing on basic biomedicine, metabolic syndrome, diet nutrients, and clinical trials. Meanwhile, I published several English biomedical articles in SCI journals. I was a scientific editor in China. Thus, I'm quite good at scientific writing both in Chinese and English, as well as translation in those areas.
Keywords: Chinese, Medical writing, Biology, Biomedicine, Biostatistics, Clinical trials, Meta-analysis, Nutrition, Dietary supplements, Metabolic syndrome, History