Mar 23, 2007 15:27
17 yrs ago
English term
AbM definition
English to Russian
Science
Biology (-tech,-chem,micro-)
The CDRs of the murine H8 antibody were identified using the AbM definition, which is based on sequence variability as well as the location of the structural loop regions.
Proposed translations
(Russian)
3 +2 | определение на основе модели антитела | Pavel Venediktov |
4 | программное моделирование антител | salavat |
Proposed translations
+2
9 mins
Selected
определение на основе модели антитела
A number if definitions of the CDRs are commonly in use:
The Kabat definition is based on sequence variability and is the most commonly used.
The Chothia definition is based on the location of the structural loop regions.
The AbM definition is a compromise between the two used by Oxford Molecular's AbM antibody modelling software.
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Note added at 10 мин (2007-03-23 15:38:41 GMT)
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Ссылка на источник:
http://www.biochem.ucl.ac.uk/~martin/abs/GeneralInfo.html
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Note added at 20 мин (2007-03-23 15:47:54 GMT)
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Вроде действительно так. Здесь сказано напрямую:
An improved antibody modelling algorithm has been developed which incorporates significant improvements to the earlier versions developed by Martin et al. (1989, 1991), Pedersen et al. (1992) and Rees et al. (1996) and known as AbM (Oxford Molecular).
http://peds.oxfordjournals.org/cgi/content/full/13/12/819
The Kabat definition is based on sequence variability and is the most commonly used.
The Chothia definition is based on the location of the structural loop regions.
The AbM definition is a compromise between the two used by Oxford Molecular's AbM antibody modelling software.
--------------------------------------------------
Note added at 10 мин (2007-03-23 15:38:41 GMT)
--------------------------------------------------
Ссылка на источник:
http://www.biochem.ucl.ac.uk/~martin/abs/GeneralInfo.html
--------------------------------------------------
Note added at 20 мин (2007-03-23 15:47:54 GMT)
--------------------------------------------------
Вроде действительно так. Здесь сказано напрямую:
An improved antibody modelling algorithm has been developed which incorporates significant improvements to the earlier versions developed by Martin et al. (1989, 1991), Pedersen et al. (1992) and Rees et al. (1996) and known as AbM (Oxford Molecular).
http://peds.oxfordjournals.org/cgi/content/full/13/12/819
4 KudoZ points awarded for this answer.
Comment: "Selected automatically based on peer agreement."
12 mins
программное моделирование антител
http://www.biochem.ucl.ac.uk/~martin/abs/GeneralInfo.html
AbM antibody modelling software.
AbM antibody modelling software.
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