English to Russian Medical Medical: Pharmaceuticals клинические испытания

Previous trials showed the duration of action defined in the protocol tended to be delayed in consideration of the pharmacokinetic data on the end of exposure and the pharmacodynamic data on the end of action, and this definition based on blood glucose seemed to be inappropriate as the duration of action.

Помогите пожалуйста понять в чем отличие этих терминов в данном контексте?