https://www.proz.com/kudoz/english-to-french/medical-general/5379100-unresolved-rejection.html

Glossary entry

English term or phrase:

unresolved rejection

French translation:

rejet inexpliqué (ou en cours)

Added to glossary by Drmanu49
Nov 5, 2013 15:51
10 yrs ago
3 viewers *
English term

unresolved rejection

English to French Medical Medical (general) étude clinique/greffe
Histological evidence of unresolved rejection requiring treatment or expected to require treatment during the study period
Proposed translations (French)
4 +3 rejet inexpliqué
Change log

Nov 6, 2013 15:55: Drmanu49 Created KOG entry

Proposed translations

+3
1 min
Selected

rejet inexpliqué

IMO

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Note added at 1 minute (2013-11-05 15:53:13 GMT)
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La greffe du rein : les premiers pas de la transplantation d'organes ...
www.letelegramme.fr/.../la-greffe-du-rein-les-premiers-pas-...
2 juil. 2012 - Il retrace pour nous, l'histoire de la greffe de rein. ... Le phénomène de rejet, encore inexpliqué à l'époque, fit une nouvelle victime », poursuit ...

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Note added at 2 minutes (2013-11-05 15:53:52 GMT)
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voir caractéristique inexpliquée du rejet

Comment les lymphocytes T rejettent-ils les greffes de rein
www.soc-nephrologie.org/PDF/enephro/publications/.../2009_0...
de G EinEckE - ‎Autres articles
particulièrement délétère dans le pronostic de la greffe. il existe deux types de .... Une caractéristique inexpliquée du rejet est que les lymphocytes T activés par.

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Note added at 1 jour4 minutes (2013-11-06 15:56:19 GMT) Post-grading
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Je suis d'accord avec la note d'Helen, ceci pourrait aussi être une phase de rejet non résolue donc en cours.
Peer comment(s):

agree Christian Fournier
18 mins
Thank you Christian.
agree Philippe Locquet
33 mins
Thank you.
agree Platary (X)
1 hr
Thank you Adrien.
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4 KudoZ points awarded for this answer. Comment: "Merci à tous"

Reference comments

4 hrs
Reference:

ongoing

I don't translate into French, so I'm afraid I can't suggest a translation for this, but I understand that "unresolved" means that there is histological evidence that rejection is ongoing (despite immunosuppressant therapy for acute rejection). For example:

"The biopsies are graded in the following manner: (a) Mild acute rejection is characterized by a perivascular and mild interstitial infiltrate of pyroninophilic lymphoblasts wihtout myocyte necrosis. (b) Moderate acute rejection has an increased infiltrate extending into the interstitium and causing focal myocyte necrosis. This requires augmentation of immunosuppression. (c) Severe acute rejection, which is more difficult to reverse, includes a more prolific infiltrate with the addition of neutrophils, hemorrhage, and increased myocyte necrosis. (d) Ongoing acute rejection implies that the degree of acute rejection is the same, or worse, than the previous biopsy. (e) Resolving or resolved acute rejection shows reparative changes with diminishing or absent inflammatory infiltrate following treatment.
http://link.springer.com/article/10.1007/BF02072369
Peer comments on this reference comment:

agree marie-christine périé : Hi Helen !
12 hrs
Hi Marie-Christine :-)
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