Member since May '05 Working languages: English to Spanish Spanish to English |  Alicia Casal Certified Translator and Interpreter Buenos Aires, Distrito Federal, Argentina Local time: 08:54 ART (GMT-3)
Native in: Spanish | |
Your partner to success! | Freelancer, Verified member | | Blue Board: Anagram Translations / Alicia Casal | | Translation, Interpreting, Editing/proofreading, Website localization, Software localization, Subtitling, Post-editing, Transcription, Training, Desktop publishing, Project management, Vendor management, Sales, Operations management | | Specializes in: | | Internet, e-Commerce | Computers (general) | | Education / Pedagogy | Government / Politics | | Law (general) | Medical (general) | | Telecom(munications) | Tourism & Travel |
| Also works in: | | Automation & Robotics | Business/Commerce (general) | | Law: Contract(s) | Law: Patents, Trademarks, Copyright | | Marketing / Market Research | Media / Multimedia | | Medical: Pharmaceuticals | Medical: Instruments | | Medical: Health Care | Psychology | | Real Estate | Religion | | Social Science, Sociology, Ethics, etc. | Law: Taxation & Customs | | Investment / Securities | Journalism | | Medical: Dentistry | Computers: Software | | Finance (general) | Computers: Systems, Networks | | Human Resources | IT (Information Technology) | | Medical: Cardiology | Insurance | | International Org/Dev/Coop |
More Less | English to Spanish - Rates: 0.09 - 0.10 USD per word / 35 - 40 USD per hour Spanish to English - Rates: 0.10 - 0.10 USD per word / 40 - 40 USD per hour | | PRO-level points: 340, Questions answered: 380, Questions asked: 51 | Sample translations submitted: 2 | English to Spanish: Microbiology | Source text - English MICROBIOLOGY
Mechanism of Action
Emtricitabine: Emtricitabine, a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. Emtricitabine 5'-triphosphate inhibits the activity of the HIVtermination. Emtricitabine 5′-triphosphate is a weak inhibitor of mammalian DNA polymerase , , and mitochondrial DNA polymerase .
Tenofovir disoproxil fumarate: Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. Tenofovir disoproxil fumarate requires initial diester hydrolysis for conversion to tenofovir and subsequent phosphorylations by cellular enzymes to form tenofovir diphosphate. Tenofovir diphosphate inhibits the activity of HIV-1 RT by competing with the natural substrate deoxyadenosine 5′-triphosphate and, after incorporation into DNA, by DNA chain termination. Tenofovir diphosphate is a weak inhibitor of mammalian DNA polymerases , , and mitochondrial DNA polymerase .
Antiviral Activity
Emtricitabine and tenofovir disoproxil fumarate: In combination studies evaluating the in vitro antiviral activity of emtricitabine and tenofovir together, synergistic antiviral effects were observed.
Emtricitabine: The in vitro antiviral activity of emtricitabine against laboratory and clinical isolates of HIV was assessed in lymphoblastoid cell lines, the MAGI-CCR5 cell line, and peripheral blood mononuclear cells. The IC50 values for emtricitabine were in the range of 0.00130.64 μM (0.00030.158 μg/mL). In drug combination studies of emtricitabine with nucleoside reverse transcriptase inhibitors (abacavir, lamivudine, stavudine, zalcitabine, zidovudine), non-nucleoside reverse transcriptase inhibitors (delavirdine, efavirenz, nevirapine), and protease inhibitors (amprenavir, nelfinavir, ritonavir, saquinavir), additive to synergistic effects were observed. Most of these drug combinations have not been studied in humans. Emtricitabine displayed antiviral activity in vitro against HIV-1 clades A, B, C, D, E, F, and G (IC50 values ranged from 0.0070.075 μM) and showed strain specific activity against HIV-2 (IC50 values ranged from 0.0071.5 μM).
| Translation - Spanish MICROBIOLOGÍA
Mecanismo de Acción
Emtricitabina: Emtricitabina, un análogo nucleósido sintético de la citidina, es fosforilada con enzimas celulares para formar emtricitabina 5'-trifosfato. Emtricitabina 5'-trifosfato inhibe la actividad de la transcriptasa inversa del VIH-1 compitiendo con el sustrato natural de deoxicitidina 5’-trifosfato y al ser incorporada al ADN viral naciente que resulta en la terminación de la cadena. Emtricitabina 5’-trifosfato es una inhibidor débil de las polimerasas , , del ADN de los mamíferos y de la polimerasa del ADN mitocondrial.
Tenofovir disoproxil fumarato: El tenofovir disoproxil fumarato es un análogo nucleósido fosfonato diéster acíclico del monofosfato de adenosina. El tenofovir disoproxil fumarato requiere una hidrólisis inicial del diéster para convertirse en tenofovir y subsiguientes fosforilaciones mediante enzimas celulares para formar el tenofovir difosfato. El tenofovir difosfato inhibe la actividad de la transcriptasa inversa del VIH-1 al competir con el sustrato natural deoxiadenosina 5’-trifosfato y, luego de su incorporación al ADN, mediante la terminación de la cadena de ADN.
Tenofovir difosfato es un inhibidor débil de las polimerasas , , del ADN de los mamíferos y de la polimerasa del ADN mitocondrial.
Actividad Antiviral
Emtricitabina y tenofovir disoproxil fumarato: En estudios de combinación que evaluaban la actividad antiviral in vitro de la emtricitabina y el tenofovir en conjunto, se observaron efectos antivirales sinergísticos.
Emtricitabina: La actividad antiviral in vitro de la emtricitabina con respecto a aislados de laboratorio y aislados clínicos de VIH se evaluó en líneas de células linfoblastoideas, en la línea de células MAGI-CCR5 y en células mononucleares sanguíneas periféricas. Los valores IC50 para la emtricitabina estuvieron dentro del rango de 0,0013-0,64 mM (0,0003-0,158 mg/mL). En estudios de combinación de drogas sobre la emtricitabina con inhibidores nucleósidos de la transcriptasa inversa (abacavir, lamivudina, estavudina, zalcitabina, zidovudina), inhibidores no nucleósidos de la transcriptasa inversa (delavirdina, efavirenz, nevirapina), e inhibidores de la proteasa (amprenavir, nelfinavir, ritonavir, saquinavir), se observaron aditivos a los efectos sinergísticos. La mayoría de estas combinaciones de drogas no se estudiaron en humanos. Emtricitabina presentó una actividad antiviral in vitro con respecto a los clades A, B, C, D, E, F y G del VIH-1 (los valores IC50 oscilaron entre 0,007-0,075 mM) y mostraron una actividad específica de las cepas respecto del VIH-2 (los valores IC50 oscilaron entre 0,007-1,5 mM).
| | English to Spanish: Consent to medical and surgical procedures | Source text - English ENGLISH VERSION:
CONSENT TO MEDICAL AND SURGICAL PROCEDURES: The undersigned consents to
the procedures which may be performed during this hospitalization or on an outpatient
basis, including treatment or services, and which may include but are not limited to
laboratory procedures, x-ray examination, medical or surgical treatment or procedures,
anesthesia, or hospital services rendered the patient under the general and special
instructions of the patient’s physician or surgeon.
NURSING CARE: This hospital provides only general duty nursing care. If the patient’s
condition is such as to need the service of a special duty nurse, it is agreed that such must
be arranged by the patient or his/her legal representative. The hospital shall in no way be
responsible for failure to provide the same and is hereby released from any and all liability
arising from the fact that said patient is not provided with such additional care.
| Translation - Spanish SPANISH VERSION:
CONSENTIMIENTO PARA PROCEDIMIENTOS MÉDICOS Y QUIRÚRGICOS: El
que suscribe otorga su consentimiento para que se lleven a cabo los procedimientos
necesarios durante su internación, incluyendo tratamientos o servicios, que abarcan pero no
se limitan a procedimientos de laboratorio, radiología, tratamientos o procedimientos
médicos o quirúrgicos, anestesia, o bien servicios hospitalarios brindados al paciente de
acuerdo con las instrucciones del médico o cirujano tratantes.
SERVICIOS DE ENFERMERÍA: Este hospital provee servicios generales de enfermería. Si
la condición del paciente requiriere servicios especiales de enfermería, se acuerda que el
paciente o su representante legal hará las gestiones pertinentes. El hospital no será, bajo
ninguna circunstancia, responsable si éstos no son provistos y por medio del presente
deslinda toda responsabilidad que pudiere surgir por la falta de cuidados adicionales para el
paciente. | More Less | | Alicia | | Master's degree - UCA | | Years of translation experience: 25. Registered at ProZ.com: Jan 2005. Became a member: May 2005. | English to Spanish (Colegio de Traductores Públicos de la Ciudad de Buenos Aires, verified) Spanish to English (Colegio de Traductores Públicos de la Ciudad de Buenos Aires, verified) | | CTPCBA | | ANAGRAM Translations | | Adobe Acrobat, Adobe Illustrator, Adobe Photoshop, Dreamweaver, FrameMaker, Frontpage, Indesign, Microsoft Excel, Microsoft Word, Abby Fine Reader, Adobe Acrobat 7.0 PRO, Express Scribe, Infix, Pagemaker, Passolo, Powerpoint, QuarkXPress, SDL TRADOS, SDLX, Wordfast | | http://www.anagramtranslations.com.ar | | English (RTF) | | Alicia Casal endorses ProZ.com's Professional Guidelines. | | About me Sworn Translator: Graduated from Universidad Católica Argentina
Graduated from Universidad Católica Argentina.
Intepreter: Emilio Stevanovitch
French Translator: Graduated from Alianza Francesa, Buenos Aires.
Spanish Teacher: Graduated from Universidad de Buenos Aires.
M.A. in Marketing: Graduated from Universidad de Belgrano, Buenos Aires.
M. A. in Management: Graduated from Universidad de Belgrano, Buenos Aires.
I' m one of the partners of a TEAM OF FREELANCE TRANSLATORS: WE ARE NOT AN AGENCY.
-I.T. (Hardware, Software, Systems)
-Web Site Translations and Adaptations
-Telecommunications
-Health Care/ Health Care Plans/ Insurances
-Medicine General
-Cardiology
-Oncology
-Toxicology
-Plastic Surgery, etc.
-Odontology
-Legal; Sworn Translations
-Government and Politics
SERVICES:
-Translation
-Project Management
-Transcription and Translation
-Adaptation (Advertising)
-Proof Reading
-Editing
-Localization
-Voiceover
-QuarkXpress, InDesgin, Autocad, etc.
-Project Mangement
-DTP:
http://www.anagramtranslations.com.ar/dtp_services.html
-Tourist Assitance
- Interpreting
CoursSpanish as a Foreign Language; D.E.L.E. Exam Professores: Spanish as a
Foreign Language, Business Spanish, etc.
Legal English Certificate Courses
References upon demand.
For further information please go to:
www.anagramtranslations.com.ar
Member of CTPCBA s International Relations Committee

Professional Experience
In House Experience: Project Leader and Coordinator:
* Trade Baires: Freight Forwarder and Logistics Company
* Movicom: Mobile Telecommunications Corporation
* Arquinauta.Com: Construction Dot.Com and IT services.
* Hospital Alemán: Private Healthcare Institution
* Miniphone (Telecom and Telefónica): Telecommunications Corporation
* Docthos/HSBC Group: Private Healthcare Institution and Bank/ Insurances
* Tim SA: Private Healthcare Holding
* Cim SA: Private Healthcare Company
* La Razón: Newspaper (Buenos Aires, Argentina)
Language Pairs
English-Spanish; Spanish-English; French-Spanish; French-English; Spanish-Spanish.
www.anagramtranslations.com.ar
Being experienced linguists, we translate from and into every Spanish variant.
SOME OF OUR PROJECTS:
Government & Politics:
• Translators for highly important Law Firm in Washington, D.C. in major lawsuit. 900.000 words. Spanish>English
• Translation of Canditates’ Statements for California
• State. English>Spanish.
. U.N.E.S.C.O. English>Spanish 12.400 words
I.T.:
• Network Rearrangements: 11.500 words. English>Spanish
• HP-UX System and Network Administration III. English>Spanish
• Major design software for engineers: 120.000 words in Excel files with TagEditor. English>Spanish (NDA)
Web Sites’ Translations:
• Agrochemicals Website: www.agropecuariamh.com.ar Spanish>English
• Lodging in San Martín de los Andes: www.laaraucanalodge.com Spanish>English
. http://www.ngbroadcasting.com : English>Spanish
Medicine, Pharmacology and Health Care:
. Allergy and Asthma: Symptoms and Treatment. 12.000 words
. Beta Blockers for arrhytmia. 20.000 words
. Stent Procedure and Angioplasty. 6.800 words
. Cosmetic Dentistry. Bleaching. 4.200 words
. Rosacea. 8.300 words.
. Argentine Private Health System. 25.000 words
. Anemia. Iron deficiency. 5.600 words
. HIV and Hepatitis B prevention. 7.000 words
. Mammary Implants 15.340 words
. Plans and Services. (Private Healthcare Group) 12.500 words
. Breast Cancer Prevention. 4.800 words
. Second Generation Anti-Depressives. 19.000 words
. Plastic Sugery. Laser. Laserlipolisis. 35.000 words
. “Pazopanib” Clinical Research. 24.000 words
. LABORATORY SOP (Standard Operating Procedures): Organization & Personnel; Log books; Records keeping; Reagent Labelling; Preparation, Revision and Approval of SOP; Samples (15.000 words)
. Modern Physiotherapy in Patients with CF; International Nurse Specialist Group: www.cfww.org Worcester, Massachussets
. SERVICE AGREEMENT: Study serotyping and antibiogram (the “Study”) of strains from patients with invasive diseases that have developed Streptococcus pneumoniae or Haemophilus influenzae in several puncture liquids or fluids. 7.500 words
Sworn Translations:
• Birth certificates. Spanish>English
• Academic transcripts. Spanish>English
• Certificado de Libre Venta. Certificate of Free Sale. Spanish>English
Chemistry
. Shell lubricants test.Eng>Spa, 4500 words.
Engineering:
• I.D. Systems, Inc. – Wan Console 1,5
• Ford Training Documents. English>”Mexican” Spanish: 15.000 words
Financial
. Autodesk: Study of Transfer Prices. Spanish>English: 27.000 words
. Western Union: Bank Account Procedures. English>Spanish: 8.200 words
Legal
. Lawsuit Supermercados Disco: Spanish>English: 8.400 words
. N.D.A. NGB Broadcasting. English>Spanish
Marketing and Advertising
. T.V. Scripts. Coca-Cola
. Advertising Spots. Toyota
. Customer Presentation. NGB Broadcasting. English>Spanish
. Co-operation Agreeement. English>Spanish. NGB Broadcasting.
. Relief artwork (flyer). Spanish>English
Human Resources
. Hay Group. Eng.>Spa: 45.000 words
Transcription and Translation:
• Helpline of pharmaceutical company. “Mexican” Spanish>English / Spanish>English
Translation and voicing:
• Leading Pharmaceutical Company Helpline: English>Spanish / Spanish recording
Editing and Proofreading:
• Laboratory Standard Operation Procedures (SOP): Equipment and Maintenance, Logbooks, Organization and Personnel, Records Keeping, Reagent Labelling, Samples, Management, CAPA.
• SAGIMA, Dental Instruments manufacturer’s brochure.
SOME OF OUR DIRECT CLIENTS:
.Nextel
.NGB Broadcasting Corporation
.Instituto Cardiovascular Buenos Aires
.Devas. Cosmiatry
.Polux. Advertising
.Belleze. Plastic Surgery
.Universidad Rey Juan Carlos. Madrid
.Ford
.H.S.B.C.
.Amclean
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