Glossary entry

German term or phrase:

Inzidenzdichte

English translation:

force of morbidity

Added to glossary by Peter Zauner
Aug 4, 2022 11:32
1 yr ago
24 viewers *
German term

Inzidenzdichte

German to English Science Medical: Pharmaceuticals Statistics
All,

I am translating a prospective post-marketing surveillance study titled "Tolerability of Icelandic Moss Lozenges in Upper Respiratory Tract Diseases - Multicentric Drug Monitoring Study with 3,143 Children".
The Study is from Germany and was published in 2004.

The passage in question reads:

Die Obergrenzen der hierfür in Tabelle 3 angegebenen 95%-Konfidenzintervalle zeigen, dass alle berichteten unerwünschten Arzneimittelwirkungen in der Population bei weniger als 2,5‰ der mit Produkt X oder Produkt Y behandelten Fälle zu erwarten sind. Für Ereignisse, die im Rahmen der Anwendungsbeobachtung überhaupt nicht beobachtet wurden, wurde als Obergrenze des 95%-Konfidenzintervalls 1,2‰ bestimmt. Die ***Inzidenzdichte*** für unerwünschte Arzneimittelwirkungen wurde mit 7 Ereignissen in 21058 Patienten-Tagen auf 0,00033 (95%-Konfidenzintervall: 0,00013-0,00068) Ereignisse pro Behandlungstag bzw. auf eine unerwünschte Arzneimittelwirkung je 3008 (1504-7019) Behandlungstage geschätzt.

I will appreciate any suggestions.

Many thanks.

Peter
References
see

Proposed translations

+4
9 mins
Selected

force of morbidity

Die Inzidenzdichte (auch Force of Morbidity) ist ein Maß für die Intensität bzw. "Geschwindigkeit" des Erkrankungsgeschehens. In allgemeinster Form bezieht sie die Anzahl der Inzidenzfälle auf die (gesunde) Personenzeit unter Risiko der betrachteten Bevölkerung im betrachteten Zeitraum.

GBE-Glossar - RKIhttps://www.rki.de › Glossar › gbe_glossar_catalog

https://www.peoi.org/Courses/Coursesen/phfoundation/ch/ch8a....

https://www.rki.de/DE/Content/Gesundheitsmonitoring/Gesundhe...
Peer comment(s):

agree Simon Vigneault
6 mins
agree Susanne Schiewe
28 mins
agree liz askew
5 hrs
agree Cillie Swart : seems plausible
5 hrs
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you! "
+3
1 hr

incidence density/incidence rate

I have seen it so far only as 'incidence density'.

However I found the following:
Incidence density - synonym for incidence rate
Incidence rate - Number of incident events divided by the cumulative at-risk time in the sample: a time-constant incidence ‘force’ (hazard)
https://link.springer.com/article/10.1007/s00134-014-3279-7

Examples:
Incidence density is defined as the number of incident cases occurring in a susceptible population followed over a given time period; its units are therefore expressed as the number of cases per unit of person time. For example, if four cases of a disease occur in a population of 1000 people followed for one year, the incidence density for this disease in this particular population would be 4 cases per 1000 person years. The incidence density ratio is defined as the ratio of incidence density of an exposed group to that of an unexposed group. In the example above, if the group described had been exposed to a particular agent and if the incidence density of a comparable unexposed group were 2 cases per 1000 person years, the incidence density ratio of these two groups would be equal to 2 (4 per 1000 person years/2 per 1000 person years). As noted above, the odds ratio has been shown to be an unbiased estimator of this incidence density ratio. (1) Consequently, there is usually no need to invoke the rare disease assumption or to consider the odds ratio as being an approximation to the rate ratio.
https://www.bmj.com/content/320/7233/503/related

The national cost of adverse events in adult inpatients was estimated as the product of (1) the estimated number of adverse events—using the INAES incidence density of adverse events applied to the number of adult inpatient admissions to acute public hospitals in 2009, excluding those with obstetric and psychiatric principal diagnoses (n=339,84434); and (2) the average cost of an event—calculated as the INAES mean number of added bed days attributed to adverse events multiplied by the average cost of an inpatient hospital bed in Ireland in 2009 (€909 per day36).
https://qualitysafety.bmj.com/content/26/2/111

Peer comment(s):

agree philgoddard : If there's an exact and obvious English equivalent, you might as well use it.
17 mins
Thank you!
agree Dr. Christopher Kronen
27 mins
Thank you!
agree liz askew
3 hrs
Thank you!
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Reference comments

1 hr
Reference:

see

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