Glossary entry

Spanish term or phrase:

vvd

English translation:

volume of medium per reactor volume per day

Added to glossary by Charles Davis
Oct 13, 2014 13:46
9 yrs ago
3 viewers *
Spanish term

vvd

Spanish to English Medical Biology (-tech,-chem,micro-)
In a description of a monoclonal antibody production process:

La velocidad de dilución se manipula en un intervalo entre 0,25 y 2 vvd en función de la concentración celular.

Thanks!
Change log

Oct 27, 2014 07:41: Charles Davis Created KOG entry

Proposed translations

+2
7 hrs
Selected

volume of medium per reactor volume per day

It works in both languages: volumen por volumen por día or volume per volume per day. It's a measure of perfusion rate.

"La expresión “velocidad de dilución”, según se define en la presente, se refiere a la velocidad de dilución D expresada en vvd, calculada como litro de medio por litro de volumen de trabajo del sistema total por día (volumen total = lecho cargado + volumen del tanque de acondicionamiento) [...]
Unas velocidades de perfusión iniciales de aproximadamente 2,6 ó 2,5 ó 2,75 vvd han demostrado ser particularmente ventajosas."
http://www.oepm.es/pdf/ES/0000/000/02/37/04/ES-2370417_T3.pd...

"A control strategy for perfusion rate (volume of fresh medium/working volume of reactor/day, vvd) was identified as a key factor affecting cell growth"
http://www.ncbi.nlm.nih.gov/pubmed/17269696

"Furthermore, the significance of the control strategy of perfusion rate (volume of fresh medium/working volume of reactor/day, vvd) was investigated."
http://www.ncbi.nlm.nih.gov/pubmed/15903251

"The perfusion rate in a perfusion run is generally reported
as VVD (volume of medium perfused per bioreactor
volume per day)."
http://www.biomedcentral.com/content/pdf/1753-6561-7-S6-P89....
Peer comment(s):

agree María Zavarse
5 hrs
Thank you, magazavarse :)
agree Neil Ashby : Good one Charles
11 hrs
Many thanks, Neil. All the best ;)
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4 KudoZ points awarded for this answer. Comment: "Selected automatically based on peer agreement."
17 mins

sentence

The dilution is handled in a 0.25-2 vvd interval,depending on the cell concentration
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22 mins

vascular volume of distribution

Abbreviation is vvd in English as well.

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Note added at 36 mins (2014-10-13 14:22:37 GMT)
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Meant acronym is the same in English. It's been a long day :-)
Peer comment(s):

neutral Neil Ashby : You meant "initialism", acronyms are pronounced as words not the individual letters, compare "FIFA" with the "UN", acronym v initialism ;@)
18 hrs
Thanks, looks like I was even more tired than I thought! :-)
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Reference comments

7 hrs
Reference:

findings

A perfusion culture system using a stirred ceramic ...
www.researchgate.net/.../7838871_A_perfusion_culture_system...
A perfusion culture system using a stirred ceramic membrane reactor for ... strategy of perfusion rate (volume of fresh medium/working volume of reactor/day, vvd) was ... for a cultivation infected before maximum cell concentration was reached.
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