the connection with the transmembrane membrane preceding the NS1 protein

English to Russian Science Biology (-tech,-chem,micro-) иммунология�

As exemplified by Rab G protein, the encoded protein by the insert only contains near the C terminus a transmembrane domain which is followed by an peptide which resides in the cytosol. To achieve this configuration, the N terminal signal peptide of Rab G has been removed (or made non-functional). Based on this principle any immunogenic protein can be presented via the vector of the present invention that the protein lacks an N terminal membrane targeted domain and contains at the C terminus a targeting membrane followed by a cytoplasmic sequence to allow ***the connection with the transmembrane membrane preceding the NS1 protein***.