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  3. Chemistry; Chem Sci/Eng

reversed exposure

Spanish translation: exposición inversa o invertida

14:57 Jun 26, 2006
English to Spanish translations [PRO]
Science - Chemistry; Chem Sci/Eng
English term or phrase: reversed exposure
DM-4103 was dissolved in DMSO and administered to male rats at doses of 100 and 500 mg/kg by single subcutaneous administration, since DM-4103 is insoluble in water and is re-crystallized when mixed with serum or injected intravenously. DM-4103 did not show any notable toxicity at 100 mg/kg (Cmax: 54 g/mL, AUC24h: 743 g•h/mL) or at 500 mg/kg (Cmax: 26 g/mL, AUC24h: 319 g•h/mL). The reversed exposure observed in this study was due to the reversed absorption amount, higher at 100 mg/kg and lower at 500 mg/kg, due to re-crystallization of DM-4103 at the injection site. DM-4107 was also dissolved in DMSO and subcutaneously administered to male rats at single doses of 100 and 500 mg/kg. No toxicity was noted and the serum level of DM-4107 increased with dose elevation, with a Cmax 310 g/mL and an AUC24h of 3906 µg•h/mL.
Guillermo Ferrero
Argentina
Local time: 01:27
Spanish translation:exposición inversa o invertida
Explanation:
una traducción de reversed es inversa, lo que me parece queda mejor en el contexto.
Selected response from:

Roxanna Delgado
United States
Local time: 00:27
Grading comment
Sí, elegí "inversa". Muchas gracias!!! d=)
3 KudoZ points were awarded for this answer



Summary of answers provided
3 +1exposición inversa o invertida
Roxanna Delgado
4 -1exposición revertida (reversada)
Sergio Gaymer


  

Answers


17 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): -1
exposición revertida (reversada)


Explanation:
:)

Sergio Gaymer
Chile
Local time: 22:27
Native speaker of: Spanish
PRO pts in category: 26

Peer comments on this answer (and responses from the answerer)
disagree  Roxanna Delgado: "reversada" no existe según el DRAE.
2 hrs
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2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +1
exposición inversa o invertida


Explanation:
una traducción de reversed es inversa, lo que me parece queda mejor en el contexto.

Roxanna Delgado
United States
Local time: 00:27
Native speaker of: Native in SpanishSpanish
PRO pts in category: 3
Grading comment
Sí, elegí "inversa". Muchas gracias!!! d=)

Peer comments on this answer (and responses from the answerer)
agree  Egmont
1 hr
  -> Gracias Egmont
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