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Jun 16, 2013 17:07
11 yrs ago
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English term
Koen Speetjens (X)
spending
English to Norwegian
Science
Mathematics & Statistics
Står i de statistiske metodene for en klinisk studie:
"To maintain an overall significance level of 0.05, the treatment effect will be tested at a two-sided significance level of 0.0499, accounting for the alpha spending of 0.0001 in the interim futility analysis."
Jeg fant følgende forklaring på engelsk (http://www.statistics.com/index.php?page=glossary&term_id=41...
"Alpha Spending Function:
In the interim monitoring of clinical trials, multiple looks are taken at the accruing results. In such circumstances, akin to multiple testing, the alpha-value at each look must be adjusted in order to preserve the overall Type-1 Error. Alpha spending functions, (the Pocock family is one such set; the Lan-Demets spending function a more specific case) establish these adjusted alpha-values for each interim monitoring point, given the overall alpha. Typically, they establish relatively high alpha-values for early looks, and lower alpha-values for later looks. Thus, they constitute "stopping boundaries," which, when crossed, indicate that statistical significance has been established."
"To maintain an overall significance level of 0.05, the treatment effect will be tested at a two-sided significance level of 0.0499, accounting for the alpha spending of 0.0001 in the interim futility analysis."
Jeg fant følgende forklaring på engelsk (http://www.statistics.com/index.php?page=glossary&term_id=41...
"Alpha Spending Function:
In the interim monitoring of clinical trials, multiple looks are taken at the accruing results. In such circumstances, akin to multiple testing, the alpha-value at each look must be adjusted in order to preserve the overall Type-1 Error. Alpha spending functions, (the Pocock family is one such set; the Lan-Demets spending function a more specific case) establish these adjusted alpha-values for each interim monitoring point, given the overall alpha. Typically, they establish relatively high alpha-values for early looks, and lower alpha-values for later looks. Thus, they constitute "stopping boundaries," which, when crossed, indicate that statistical significance has been established."
Change log
Jun 16, 2013 17:17: Koen Speetjens (X) changed "Language pair" from "English to Dutch" to "English to Norwegian"
Reference comments
6 hrs
conniebrathen
Native in English
&
Norwegian
Specializes in field
Medical translations and more
Native in: Norwegian 
, English
Works in: English to Norwegian, Norwegian to English, English to Norwegian (Bokmal), and 1 more.
Reference:
Hi Koen,
I had no luck finding a Norwegian term for this, but I did find a Norwegian reference and several Swedish ones where the English term is used:
I had no luck finding a Norwegian term for this, but I did find a Norwegian reference and several Swedish ones where the English term is used:
Discussion
The nearest single verbs may be "assign" or "allocate" (the alpha significance available - typically 5% or 1%).
Which GT tells me, for better or worse, is "tildele" eller "fordele" alfa tilgjengelig betydning. In GT's defence, it's often quite good on short technical terms as long a human handles the Grammar.
Can you translate it for me? :-)
But that you already knew.
Especially because I don't understand it.
Here it looks like it really means spending as in spending money: "consommation" and "dépense", which is (as far as my limited knowledge and an online dictionary proudly states) "forbruk" and "utgifter". I can't make any sense of it in this context.
@ DLyons, yes I found only one reference :-):
SFO utgiftene funksjon 215 og 222 har et mindreforbruk som skyldes blant annet lavere husleie enn budsjettert på ca 1,5 millioner kroner.
If you see what I mean. :-)
http://www.bydel-bjerke.oslo.kommune.no/getfile.php/bydel bj...
Leaving things like this in English is a common solution as you say!
Looks like it's left in English in both Dutch (see Barends example) and also in Swedish (which is more relevant for Norwegian): http://www.proz.com/kudoz/english_to_swedish/medical:_pharma...
https://www.google.ie/search?hl=en&as_epq=spending function&...
Also not in Norwegian in the standard online Statistics dictionaries.
Dia 18: Voorbeelden van alfa spending functies (DeMets en Lan in Statistics in Medicine, 1994)
zie ook de eropvolgende dia's
o.a. Schematisch overzicht van de stopregel van Snapinn
zie ook dia 3: Interim analyse: wat en waarom?
http://tinyurl.com/mgdxhxs