Sep 4, 2020 00:55
3 yrs ago
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English term
co-crystals
GBK
English to Portuguese
Medical
Medical (general)
Definition from
Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.
Example sentences:
In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one (Indian J Pharm Sci.)
In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. (Dove Press)
As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. (Regulatory Focus™)
Proposed translations
(Portuguese)
4 +6 | cocristais | Rafael Sousa Brazlate |
Change log
Aug 22, 2020 01:06: changed "Kudoz queue" from "In queue" to "Public"
Sep 4, 2020 00:55: changed "Stage" from "Preparation" to "Submission"
Sep 7, 2020 01:56: changed "Stage" from "Submission" to "Completion"
Proposed translations
+6
52 mins
Selected
cocristais
Definition from
Química Nova:
Cocristais são materiais cristalinos homogêneos, compostos por dois ou mais compostos em proporção estequiométrica definida e que sao sólidos em condições ambientes (25 ºC/1 atm).
Example sentences:
Ao longo das últimas décadas, os cocristais têm recebido atençao significativa por parte da indústria farmacêutica, e diversos cocristais farmacêuticos têm sido relatados. (Química Nova)
4 KudoZ points awarded for this answer.
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