rich/sparse PK

German translation: pharmakokinetisch

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:pharmacokinetic (PK)
German translation:pharmakokinetisch
Entered by: Jalapeno

01:43 Apr 19, 2006
English to German translations [PRO]
Medical - Medical (general)
English term or phrase: rich/sparse PK
one of the strings from a telephone screening program for pneumonia patients. This term only appears in the quoted sentences. My first thought was "Patientenkollektiv", but since this is an English text it has to be something else. Anyone has an idea? Thank you very much.

The Rich PK arm has been closed for this study. Please draw a Sparse PK for this subject.
Christine Lam
Local time: 13:19
PK = pharmacokinetic = pharmakokinetisch
Explanation:
pharmacokinetic

"The use of pharmacokinetic/pharmacodynamic (PK/PD) analysis in early compound..."

"PK/KD modelling of the sparse PK data available relative to a rich set of PD data was achieved using a population approach in..."

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d...

"Comments on Draft Guidance for Industry: Pharmacokinetics in Pregnancy"

"Although the guidance explicitly doesn’t intend to pursue neonatal safety, as stated in the introduction on page 4, additional data collection with permission from well-studied, motivated mothers with PK data would prove clinically valuable."

http://origin.www.fda.gov/ohrms/dockets/dockets/04d0459/04D-...

And others.

http://www.google.de/search?hl=de&lr=lang_de&sa=X&oi=spell&r...

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Note added at 4 hrs (2006-04-19 06:09:15 GMT)
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P.S. Der Google-Link führt zum deutschen Wort. Mit einer Google-Suche mit einer Kombination aus den Suchbegriffen "rich PK", "pharmacokinetic", "sparse PK" etc. lassen sich auch Belege für den englischen Begriff finden. So bin ich auf die Links oben gekommen.
Selected response from:

Jalapeno
Local time: 19:19
Grading comment
vielen Dank
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +4PK = pharmacokinetic = pharmakokinetisch
Jalapeno
4Erhebung umfangreicher/weniger Daten in pharmakokinetischer Studie
Stefan Kopp


Discussion entries: 7





  

Answers


4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +4
rich/sparse pk
PK = pharmacokinetic = pharmakokinetisch


Explanation:
pharmacokinetic

"The use of pharmacokinetic/pharmacodynamic (PK/PD) analysis in early compound..."

"PK/KD modelling of the sparse PK data available relative to a rich set of PD data was achieved using a population approach in..."

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d...

"Comments on Draft Guidance for Industry: Pharmacokinetics in Pregnancy"

"Although the guidance explicitly doesn’t intend to pursue neonatal safety, as stated in the introduction on page 4, additional data collection with permission from well-studied, motivated mothers with PK data would prove clinically valuable."

http://origin.www.fda.gov/ohrms/dockets/dockets/04d0459/04D-...

And others.

http://www.google.de/search?hl=de&lr=lang_de&sa=X&oi=spell&r...

--------------------------------------------------
Note added at 4 hrs (2006-04-19 06:09:15 GMT)
--------------------------------------------------

P.S. Der Google-Link führt zum deutschen Wort. Mit einer Google-Suche mit einer Kombination aus den Suchbegriffen "rich PK", "pharmacokinetic", "sparse PK" etc. lassen sich auch Belege für den englischen Begriff finden. So bin ich auf die Links oben gekommen.

Jalapeno
Local time: 19:19
Native speaker of: Native in GermanGerman
PRO pts in category: 8
Grading comment
vielen Dank

Peer comments on this answer (and responses from the answerer)
agree  Stefan Kopp: du nimmst mir die Übersetzung aus den Tasten
5 mins
  -> ;-)

agree  Alexandra Collins: Dem ist nichts hinzuzufügen
1 hr

agree  Ingeborg Gowans (X): can't top that
4 hrs

agree  Siegfried Armbruster
10 hrs
Login to enter a peer comment (or grade)

4 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
rich/sparse pk
Erhebung umfangreicher/weniger Daten in pharmakokinetischer Studie


Explanation:
oder so ähnlich

"P-PHARM: a population pharmacokinetic-dynamic data modeling program from Thermo Electron Corporation. Uses a two-stage procedure (rich data) and/or an EM-type algorithm (sparse data),..."


    Reference: http://www.boomer.org/pkin/soft.html
Stefan Kopp
Malaysia
Local time: 00:19
Native speaker of: Native in GermanGerman
PRO pts in category: 4
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