Glossary entry (derived from question below)
French term or phrase:
pl
English translation:
bp
Added to glossary by
Lionel_M (X)
Apr 7, 2011 14:15
13 yrs ago
5 viewers *
French term
United States
Scientist / Linguist
Native in: English (Variants: US, UK) 
Works in: French to English, Italian to English, Portuguese to English, and 2 more.
pl
French to English
Medical
Biology (-tech,-chem,micro-)
immunology
The issue here is that the abbreviation could be in French or in English, as the author mixes the two throughout the file. However, for example, 'kb' is kilbase so this could be anything and the position of 'pl' could be before the number in English or after it, depending on what it refers to. My best guess is that it refers to a base pair position in the plasmid, but I am looking for any input at all.
"Pour augmenter la combinaison de transgènes vaccinants possible, la stratégie s’impose ; elle consiste à ne conserver du virus de départ que les éléments essentiels pour la réplication-encapsidation du virus, à savoir les 2ITR (inverted Terminal Repeat de 62pl) et la séquence psi d’encapsidation (env. 200pl) ; on obtient ainsi un « espace » pour des transgènes de 43kb."
MTIA!
"Pour augmenter la combinaison de transgènes vaccinants possible, la stratégie s’impose ; elle consiste à ne conserver du virus de départ que les éléments essentiels pour la réplication-encapsidation du virus, à savoir les 2ITR (inverted Terminal Repeat de 62pl) et la séquence psi d’encapsidation (env. 200pl) ; on obtient ainsi un « espace » pour des transgènes de 43kb."
MTIA!
Proposed translations
(English)
| 3 | bp |
Lionel_M (X)
|
| 4 | bp |
Joanne Archambault
|
Change log
Apr 8, 2011 15:31: Lionel_M (X) Created KOG entry
Proposed translations
28 mins
Selected
bp
It seems to be a typo; 62 for ITR is the number of base-pair.
Also, the encapsidation sequence is about 200 nucleotides long
Origin of adenovirus DNA replication : : Role of the nuclear ... - [ Traduire cette page ]
de RT Hay - 1985 - Cité 45 fois - Autres articles
The presence of inverted terminal repeat DNA sequences gives the displaced single ..... with molecules containing either 85 bp or 62 bp of the Ad4 ITR (Fig. ...
linkinghub.elsevier.com/retrieve/pii/0022283685902633 -
A cis-acting DNA signal for encapsidation of simian virus 40. - [ Traduire cette page ]
de A Oppenheim - 1992 - Cité 35 fois - Autres articles
... virus 40 encapsidation signal).ses is present within a 200-bp DNA fragment, ... Deletion of the GC boxes and the enhancer sequences almost abolished ...
www.ncbi.nlm.nih.gov/pubmed/1323699
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Note added at 32 min (2011-04-07 14:47:43 GMT)
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En Français, ce serait pb (non pl) . "paires de bases"
Also, the encapsidation sequence is about 200 nucleotides long
Origin of adenovirus DNA replication : : Role of the nuclear ... - [ Traduire cette page ]
de RT Hay - 1985 - Cité 45 fois - Autres articles
The presence of inverted terminal repeat DNA sequences gives the displaced single ..... with molecules containing either 85 bp or 62 bp of the Ad4 ITR (Fig. ...
linkinghub.elsevier.com/retrieve/pii/0022283685902633 -
A cis-acting DNA signal for encapsidation of simian virus 40. - [ Traduire cette page ]
de A Oppenheim - 1992 - Cité 35 fois - Autres articles
... virus 40 encapsidation signal).ses is present within a 200-bp DNA fragment, ... Deletion of the GC boxes and the enhancer sequences almost abolished ...
www.ncbi.nlm.nih.gov/pubmed/1323699
--------------------------------------------------
Note added at 32 min (2011-04-07 14:47:43 GMT)
--------------------------------------------------
En Français, ce serait pb (non pl) . "paires de bases"
4 KudoZ points awarded for this answer.
Comment: "Lionel, many thanks for the prompt and thorough response/explanation. Joanne, thank you for the confirmation. It was as I suspected, and you confirmed, a repeated typo."
33 mins
Joanne Archambault
United States
United States
Native in French
&
English
Specializes in field
United States
PhD + Pharmaceutical/Orthopedics
Native in: English , French
Works in: French to English
Related KudoZ points
:
55
bp
My educated guess based on the information that you provided is that pL, refers to the number of bases (aka base pairs) in the said sequence.
So you have an ITR at each end that is 62 bp long and the encapsulation sequence (PSI cis-element) is about 200 bp long.
Oh, and I am assuming that you are asking about "pL" and not "pI"!
So you have an ITR at each end that is 62 bp long and the encapsulation sequence (PSI cis-element) is about 200 bp long.
Oh, and I am assuming that you are asking about "pL" and not "pI"!
Discussion
But I'm glad you're thinking about typo as well.
I brought a couple of paper to show that bp numer is compatible both with ITR and encap sequence.