recombinant methods

11:48 May 25, 2015
This question was closed without grading. Reason: Other

English to Russian translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: recombinant methods
In one embodiment, the polypeptides described in the present invention or generated by a method of the present invention, e.g., humanized Ig variable regions and/or polypeptides comprising humanized Ig variable regions may be produced by recombinant methods

Furthermore, although the two domains of the Fv fragment, VL and VH, are coded for by separate genes, they can be joined, using recombinant methods, by a synthetic linker that enables them to be made as a single protein chain

The polypeptides described in the present invention or generated by a method of the present invention can, for example, be synthesized using techniques known in the art. Alternatively nucleic acid molecules encoding the desired variable regions can be synthesized and the polypeptides produced by recombinant methods.

методы, основанные на технологии рекомбинантой ДНК или методы ркомбинации?

Спасибо!
dao2812


Summary of answers provided
5 +1см.
NataliiaK
4 +1рекомбинационные методы
Natalie
4рекомбинантные методы
Grigoriy Tereshchenko


Discussion entries: 4





  

Answers


3 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
рекомбинантные методы


Explanation:


Grigoriy Tereshchenko
Ukraine
Local time: 00:10
Specializes in field
Native speaker of: Native in RussianRussian, Native in UkrainianUkrainian
PRO pts in category: 12

Peer comments on this answer (and responses from the answerer)
neutral  Natalie: Рекомбинантные - продукты рекомбинации, а методы - рекомбинационные
2 mins
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5 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
рекомбинационные методы


Explanation:
*

Natalie
Poland
Local time: 23:10
Specializes in field
Native speaker of: Russian
PRO pts in category: 4329

Peer comments on this answer (and responses from the answerer)
agree  Andrey Svitanko
44 mins
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1 hr   confidence: Answerer confidence 5/5 peer agreement (net): +1
см.


Explanation:
дело в том, что методы получения например, гуманизированных антиел, одноцепочечных вариабельных фрагментов антител (scFv) методом фагового дисплея, или замена каркасных участков антител и т.д. проводят с использованием технологий рекомбинантных ДНК.
Таким образом, методы все же рекомбинантные (сокращенно от технологий рекомбинантных ДНК).
Однако, стоит отметить, что явление рекомбинации происходит в генах, кодирующих легкие и тяжелые цепи иммуноглобулинов - V(D)J-рекомбинация. Но, это явление in vivo.


NataliiaK
Ukraine
Local time: 00:10
Specializes in field
Native speaker of: Native in UkrainianUkrainian, Native in RussianRussian
PRO pts in category: 139

Peer comments on this answer (and responses from the answerer)
agree  Sergey Krasyuk
2 hrs
  -> Спасибо!
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