Sep 21, 2015 15:07
9 yrs ago
English term
BCU
English to Russian
Medical
Medical: Pharmaceuticals
Химия
Сокращение BCU в таблице параметров процесса экструзии горячего расплава (при производстве ритонавира):
S.No Process Parameter Set value Actual value
1. BCU 15C 14C
S.No Process Parameter Set value Actual value
1. BCU 15C 14C
References
BCU = Barrel Conveying Unit (?) | Oleg Lozinskiy |
Reference comments
17 mins
Reference:
BCU = Barrel Conveying Unit (?)
25882588
PHARMANEST - An International Journal of Advances in Pharmaceutical Sciences
Volume 5|Issue 6| November-December 2014
Available online: http://www.pharmanest.net
Table.1.Process parameters and Temperature ranges to be monitored during processing of Holt melt extrusion (HME)
Process attribute
Actual range
Feed rate
1 to 1.25 Kg/hour
Torque
4 Barr
Name of the zone
Temperature
Barrel Conveying Unit (BCU)
40˚± 2˚C
Zone – I
60˚C˚± 2˚C
Zone – II
80˚C˚± 2˚C
Zone – III
100˚C˚± 2˚C
Zone – IV
120˚C˚± 2˚C
Zone – V
140˚C˚± 2˚C
Zone – VI
160˚C˚± 2˚C
Zone – VII
180˚C˚± 2˚C
Die Zone
180˚C˚± 2˚C
Cooling / Chillers zone
Maintained at 2 - 5˚C (where melt will be converted into pieces of flakes)
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
--------------------------------------------------
Note added at 21 мин (2015-09-21 15:28:52 GMT)
--------------------------------------------------
Preparation of Tolvaptan Solid Dispersions by HME:
Tolvaptan solid dispersions were prepared by using different carriers like Soluplus and Copovidone (Kollidon
VA64). Thermo Fischer, HME Parma 24 - Twin Screw Model wasused for the preparation of solid dispersions with
the feed rate of 1 to 1.25 Kg/hour, Torque:4 Barr and 8 different zones of temperature as from 40°± 2°C to 175°±
2°C with cooling/chillers zone maintained at 2 - 5°C (where melt will be converted into the pieces of flakes) shown
in Table 1.
Table 1: Temperature Ranges To Be Monitored During Processing of Holt Melt Extrusion (HME):
Name of the zone Temperature
Barrel Conveying Unit (BCU) 40°C± 2°C
Zone – I 60°C± 2°C
Zone – II 80°C± 2°C
Zone – III 100°± 2°C
Zone – IV 120°C°± 2°C
Zone – V 140°C°± 2°C
Zone – VI 160°C°± 2°C
Zone – VII 175°C°± 2°C
Die Zone 175°C°± 2°C
Cooling / Chillers zone Maintained at 2 - 5°C (where melt will be converted into pieces of flakes)
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
PHARMANEST - An International Journal of Advances in Pharmaceutical Sciences
Volume 5|Issue 6| November-December 2014
Available online: http://www.pharmanest.net
Table.1.Process parameters and Temperature ranges to be monitored during processing of Holt melt extrusion (HME)
Process attribute
Actual range
Feed rate
1 to 1.25 Kg/hour
Torque
4 Barr
Name of the zone
Temperature
Barrel Conveying Unit (BCU)
40˚± 2˚C
Zone – I
60˚C˚± 2˚C
Zone – II
80˚C˚± 2˚C
Zone – III
100˚C˚± 2˚C
Zone – IV
120˚C˚± 2˚C
Zone – V
140˚C˚± 2˚C
Zone – VI
160˚C˚± 2˚C
Zone – VII
180˚C˚± 2˚C
Die Zone
180˚C˚± 2˚C
Cooling / Chillers zone
Maintained at 2 - 5˚C (where melt will be converted into pieces of flakes)
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
--------------------------------------------------
Note added at 21 мин (2015-09-21 15:28:52 GMT)
--------------------------------------------------
Preparation of Tolvaptan Solid Dispersions by HME:
Tolvaptan solid dispersions were prepared by using different carriers like Soluplus and Copovidone (Kollidon
VA64). Thermo Fischer, HME Parma 24 - Twin Screw Model wasused for the preparation of solid dispersions with
the feed rate of 1 to 1.25 Kg/hour, Torque:4 Barr and 8 different zones of temperature as from 40°± 2°C to 175°±
2°C with cooling/chillers zone maintained at 2 - 5°C (where melt will be converted into the pieces of flakes) shown
in Table 1.
Table 1: Temperature Ranges To Be Monitored During Processing of Holt Melt Extrusion (HME):
Name of the zone Temperature
Barrel Conveying Unit (BCU) 40°C± 2°C
Zone – I 60°C± 2°C
Zone – II 80°C± 2°C
Zone – III 100°± 2°C
Zone – IV 120°C°± 2°C
Zone – V 140°C°± 2°C
Zone – VI 160°C°± 2°C
Zone – VII 175°C°± 2°C
Die Zone 175°C°± 2°C
Cooling / Chillers zone Maintained at 2 - 5°C (where melt will be converted into pieces of flakes)
https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd...
Note from asker:
Да, перевожу похожую таблицу для другого фарм. препарата. |
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