English to Spanish Medical Medical: Pharmaceuticals

Estoy traduciendo un estudio titulado "Pharmacokinetics of Oral and Intravenous Melphalan during Routine Treatment of Multiple Myeloma":

"Our results from multiple myeloma patients presented here are similar to the work of Alberts et al. and Tattersall et al. using patients with different neoplasms. We have found a **very long terminal half-life for plasma [3H]**, of which only a small proportion was soluble by 10 hr. This suggests that melphalan alkylates plasma proteins extensively, the half-life of the label being approximately the same as that of plasma proteins (Fig. 2). Melphalan itself, on the other hand, decays biphasically after i.v. administration, with half-lives of 7.7 and 83 min (Table 4), values similar to those of Alberts et al., but with less scatter. However, there must be an earlier phase of distribution from the plasma to the rest of the 'central' compartment (average apparent volume = 12.81, Table 4) which is extremely rapid and is almost over by the time the first sample is taken at 5 min. The t1/2 for patient CL of 1.1 min might be an indication of this very rapid phase, the data seeming to lack the α phase."

Half-life en este caso es período de semidesintegración. No sé a qué se refiere "terminal" en este contexto.

Gracias nuevamente