Glossary entry

English term or phrase:

vh/vhh

Arabic translation:

السلسلة الثقيلة المتغيرة / المجال المتغير للسلسة الثقيلة

Added to glossary by Lamine Boukabour
Jun 13, 2023 21:18
1 yr ago
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English term

VH/VHH

English to Arabic Medical Medical (general) Medical/science
The exploration of fully human antibodies. Human single chain Antibodies , HuscFvs) or humanized nanobodies ( single - domain antibodies, sdAb, VH/VHH)
Change log

Jun 20, 2023 16:40: Lamine Boukabour Created KOG entry

Proposed translations

14 hrs
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السلسلة الثقيلة المتغيرة / المجال المتغير للسلسة الثقيلة

In the given context, "VH/VHH" refers to two different types of antibody fragments derived from human sources.

"VH" stands for "variable heavy chain," which is a component of an antibody. Antibodies are composed of two heavy chains and two light chains. The variable heavy chain is responsible for binding to specific antigens, such as pathogens or foreign substances.

"VHH" stands for "variable domain of heavy chain-only," also known as a "nanobody." Nanobodies are a type of antibody fragment derived from camelid antibodies, such as llamas or camels. They consist of a single domain derived from the heavy chain, unlike conventional antibodies that have both heavy and light chains. Nanobodies are known for their smaller size and unique properties, which make them valuable tools in research and therapeutic applications.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983233/
https://www.frontiersin.org/articles/10.3389/fimmu.2017.0160...
https://biomarkerres.biomedcentral.com/articles/10.1186/s403...
https://www.azolifesciences.com/article/VHH-Antibodies-(Nano...
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17 mins

المجال المتغير/ الأجسام المضادة ذات السلسلة الثقيلة التي تحتوي على مجال متغير

الأجسام المضادة ذات السلسلة الثقيلة التي تحتوي على مجال متغير = vhh
vh = نطاق أو مجال متغير
https://www.marefa.org/الگلوبولين_المناعي_م
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