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Turkish to English: Doktora Tezi Çalışması-Doctorate Dissertation Study General field: Science Detailed field: Medical (general)
Source text - Turkish Aromotaz eksikliği ve aromotaz gen mutasyonu ilk kez bir erkek olguda 1995 yılında otozomal resesif bir hastalık olarak tanımlandı. 1995 ve 2010 yılları arasında sekiz yeni erkek olgu bildirildi. Aromotaz eksikliği nadir görülen bir sendrom olup CYP19A1 gen mutasyonu sonucu aromotaz disfonksiyonuna bağlı estrojen sentezi azalır. Östrojenin kadın reprodüktif sistemi üzerindeki etkisi uzun yıllardır bilinmektedir fakat kadın ve erkekte estrojenin reprodüktif sistem dışı etkileri yakın zamanda tanımlandı. Son on yıldır, özellikle östrojenin erkek reprodüktif sistemi üzerindeki etkileri üzerinde durulmaktadır. Puberta sırasında büyüme ve kemik maturasyonu her iki cinsiyettede androjene bağlı olur ve androjen erkekte aromotaz ile östrojene dönüşür. Puberta sırasında, artan androjenlere bağlı östrojen seviyesi artar sonuçta kemik maturasyonu ve epifizyal kartilajda ossifikasyon gelişir. Aromotaz eksikliği sendromunda estojen eksikliğine bağlı her iki cinsiyette gecikmiş epifizyal kapanma, önikoid vücut yapısı, osteopeni ve oteoporoz gelişir.
Translation - English The aromatase deficiency and aromatase gene mutation were first defined in 1995 at a male subject as an autosomal recessive disorder. Eight new male subjects were reported between the years 1995 and 2010. The deficiency of aromatase is a rare syndrome resulting in decreased estrogen synthesis due to aromatase dysfunction as a consequence of CYP19A1 gene mutation. The effects of estrogen other than reproductive system on both male and female subjects have recently been discovered while its effect on female reproductive system being known for many years. In the past decade, it has been focused on the effects of estrogen on particularly male reproductive system. Growth and bone maturation during puberty depend on androgen in both genders and androgen is converted into estrogen in males in the presence of aromatase. During puberty, the estrogen level is increased with an increased level of androgen resulted in bone maturation and ossification of epiphyseal cartilages. Delayed epiphyseal closure, onychoid body structure, osteopenia and osteoporosis disorders are developed during aromatase deficiency syndrome in both genders resulting from estrogen deficiency.
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My name isSerhan Baran Elmaciogluand I am a mechanical engineer. I graduated from Uludag University in Turkey and shortly afterwards I moved out in the UKthen I accomplished my English education at St. Giles International London Central. Since then I have been working as a freelance translator and proofreader.Mainly, I translate from English to Turkish (my native language).
Briefly stated I have been translating different kinds of texts from the 'source language' into the 'target language', making sure that the meaning is maintained:
scientific, technical or commercial material like reports
manuals and brochures legal documents, such as contracts literary work, including novels, plays and poetry media work, such as film scripts and subtitles for films
educational resources, including textbooks, e-books and apps online content, including e-commerce, interactive platforms, business to business websites and online blogs.
If I can be of assistance, please do not hesitate to contact me.
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English to Turkish
Automotive / Cars & Trucks
Tourism & Travel
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