Feb 11, 2005 19:18
20 yrs ago
English term
three-class
English to Chinese
Other
Medical (general)
The strain of three-class antiretroviral-resistant HIV – or 3-DRC HIV – does not respond to three classes of anti-retroviral medication.
Who has time to help us find out what 3 classes refer to? IS 3-class and 3-DRC sounds like the same but what does DRC stand for?
Who has time to help us find out what 3 classes refer to? IS 3-class and 3-DRC sounds like the same but what does DRC stand for?
Proposed translations
(Chinese)
3 | NRTI, NNRTI, and PI |
Denyce Seow
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4 +1 | Suggestion |
Jianming Sun
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4 | FYI |
Lu Zou
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Proposed translations
25 mins
Selected
NRTI, NNRTI, and PI
with three classes of drugs (NRTI, NNRTI, and PI)
- NRTI: nucleoside reverse transcriptase inhibitor
- NNRTI: non-nucleoside reverse transcriptase inhibitor
- PI: protease inhibitor
I have NOOOOOOOOOO idea what DRC is.
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Note added at 35 mins (2005-02-11 19:53:54 GMT)
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DRC = detergent-resistant complex???
We have previously identified two distinct forms of putative viral assembly intermediate complexes, a detergent-resistant complex (DRC) and a detergent-sensitive complex (DSC), in human immunodeficiency virus type 1 (HIV-1)-infected CD4+ T cells (Y. M. Lee and X. F. Yu, Virology 243:78–93, 1998).
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
a detergent-resistant complex (DRC) and a detergent-sensitive complex (DSC), in human immunodeficiency virus ...
science.empas.com/search/simdoc_kisti. html?i=211961&d=A&q=%BF%AC%B7%E1%C0%FC%C1%F6
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Note added at 5 hrs 28 mins (2005-02-12 00:46:24 GMT)
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Might really be \"drug class RESISTANCE\". Check these out:
Resistance to one NNRTI leads to 抎rug class resistance
- NRTI: nucleoside reverse transcriptase inhibitor
- NNRTI: non-nucleoside reverse transcriptase inhibitor
- PI: protease inhibitor
I have NOOOOOOOOOO idea what DRC is.
--------------------------------------------------
Note added at 35 mins (2005-02-11 19:53:54 GMT)
--------------------------------------------------
DRC = detergent-resistant complex???
We have previously identified two distinct forms of putative viral assembly intermediate complexes, a detergent-resistant complex (DRC) and a detergent-sensitive complex (DSC), in human immunodeficiency virus type 1 (HIV-1)-infected CD4+ T cells (Y. M. Lee and X. F. Yu, Virology 243:78–93, 1998).
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
a detergent-resistant complex (DRC) and a detergent-sensitive complex (DSC), in human immunodeficiency virus ...
science.empas.com/search/simdoc_kisti. html?i=211961&d=A&q=%BF%AC%B7%E1%C0%FC%C1%F6
--------------------------------------------------
Note added at 5 hrs 28 mins (2005-02-12 00:46:24 GMT)
--------------------------------------------------
Might really be \"drug class RESISTANCE\". Check these out:
Resistance to one NNRTI leads to 抎rug class resistance
4 KudoZ points awarded for this answer.
Comment: "Client changed to DCR. It was a typo. Thanks to Jianming and Lu Zou too for translating the 3 classes."
+1
20 hrs
Suggestion
在我看来原文可能有些语病,照我理解就是,“the strain”为一种病毒株, 其对3类(class)抗逆转录酶病毒的(antiretroviral)药有抗性(resistant),故对这三类药不起反应。这三类药也可能就是weiweI所提的三类。我认为“three-class antiretroviral-resistant HIV”的意思是“three-class-antiretroviral-DRUG-resistant HIV”的意思。而在文中的“or 3-DRC HIV”,意为“three-class antiretroviral-resistant HIV”即“3-DRC HIV”,故客户说DRC =3 drug-class-resistant是说得通的,虽然在文字上对不起来。HIV(人体免疫缺损病毒)是一种逆转录酶病毒(retrovirus)。
2 days 3 hrs
FYI
three-class 是如weiwei所说的三种抗HIV药物,核苷类逆转录酶抑制剂,非核苷类逆转录酶抑制剂和蛋白酶抑制剂
如果该患者对这三种药物均没有反应,说明他已经出现病毒抗药,只好进行综合性的鸡尾疗法了.
如果该患者对这三种药物均没有反应,说明他已经出现病毒抗药,只好进行综合性的鸡尾疗法了.
Discussion