Feb 27, 2010 15:15
14 yrs ago
English term
Romania
Native in: Romanian 
Works in: Romanian to English, English to Italian, Romanian to Italian, and 3 more.
Mortality Acute LC50 0,00062 mg/L Fish
English to Romanian
Tech/Engineering
Science (general)
fisa tehnica de securitate
Din aceiasi fisa tehnica, daca LD inseamna doza letala, ce inseamna LC,
Proposed translations
(Romanian)
| 4 +3 | concentraţia letală pentru 50% din populaţia expusă (peşti) |
Adriana I. S.
|
References
| What does LC50 mean? |
Sandra & Kenneth Grossman
|
Proposed translations
+3
6 mins
Adriana I. S.
France
France
Native in Romanian
France
Technische Übersetzungen
Native in: Romanian 
Works in: German to Romanian, French to Romanian, English to Romanian, and 9 more.
Related KudoZ points
:
16
Selected
concentraţia letală pentru 50% din populaţia expusă (peşti)
Concentraţia unei substanţe chimice care ucide 50% din populaţia de probă.
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Note added at 1 hr (2010-02-27 16:57:18 GMT)
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toxicitatea acută acvatică LC50
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Note added at 1 hr (2010-02-27 16:57:18 GMT)
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toxicitatea acută acvatică LC50
4 KudoZ points awarded for this answer.
Comment: "Selected automatically based on peer agreement."
Reference comments
3 hrs
Sandra & Kenneth Grossman
Israel
Israel
Native in English
&
Romanian
Works in field
Israel
Quality, Reliability, Experience.
Native in: English , Romanian
Works in: French to English, Hebrew to English, Romanian to English, and 3 more.
Related KudoZ points
:
4
Reference:
What does LC50 mean?
LC stands for "Lethal Concentration". LC values usually refer to the concentration of a chemical in air but in environmental studies it can also mean the concentration of a chemical in water.
For inhalation experiments, the concentration of the chemical in air that kills 50% of the test animals in a given time (usually four hours) is the LC50 value.
Why study LD50's?
Chemicals can have a wide range of effects on our health. Depending on how the chemical will be used, many kinds of toxicity tests may be required.
Since different chemicals cause different toxic effects, comparing the toxicity of one with another is hard. We could measure the amount of a chemical that causes kidney damage, for example, but not all chemicals will damage the kidney. We could say that nerve damage is observed when 10 grams of chemical A is administered, and kidney damage is observed when 10 grams of chemical B is administered. However, this information does not tell us if A or B is more toxic because we do not know which damage is more critical or harmful.
Therefore, to compare the toxic potency or intensity of different chemicals, researchers must measure the same effect. One way is to carry out lethality testing (the LD50 tests) by measuring how much of a chemical is required to cause death. This type of test is also referred to as a "quantal" test because it is measures an effect that "occurs" or "does not occur".
Who invented the idea of an LD50?
In 1927, J.W. Trevan attempted to find a way to estimate the relative poisoning potency of drugs and medicines used at that time. He developed the LD50 test because the use of death as a "target" allows for comparisons between chemicals that poison the body in very different ways.
What are some other toxicity dose terms in common usage?
LD01 Lethal dose for 1% of the animal test population
LD100 Lethal dose for 100% of the animal test population
LDLO The lowest dose causing lethality
TDLO The lowest dose causing a toxic effect
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Note added at 3 hrs (2010-02-27 18:24:21 GMT)
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http://www.ccohs.ca/oshanswers/chemicals/ld50.html
For inhalation experiments, the concentration of the chemical in air that kills 50% of the test animals in a given time (usually four hours) is the LC50 value.
Why study LD50's?
Chemicals can have a wide range of effects on our health. Depending on how the chemical will be used, many kinds of toxicity tests may be required.
Since different chemicals cause different toxic effects, comparing the toxicity of one with another is hard. We could measure the amount of a chemical that causes kidney damage, for example, but not all chemicals will damage the kidney. We could say that nerve damage is observed when 10 grams of chemical A is administered, and kidney damage is observed when 10 grams of chemical B is administered. However, this information does not tell us if A or B is more toxic because we do not know which damage is more critical or harmful.
Therefore, to compare the toxic potency or intensity of different chemicals, researchers must measure the same effect. One way is to carry out lethality testing (the LD50 tests) by measuring how much of a chemical is required to cause death. This type of test is also referred to as a "quantal" test because it is measures an effect that "occurs" or "does not occur".
Who invented the idea of an LD50?
In 1927, J.W. Trevan attempted to find a way to estimate the relative poisoning potency of drugs and medicines used at that time. He developed the LD50 test because the use of death as a "target" allows for comparisons between chemicals that poison the body in very different ways.
What are some other toxicity dose terms in common usage?
LD01 Lethal dose for 1% of the animal test population
LD100 Lethal dose for 100% of the animal test population
LDLO The lowest dose causing lethality
TDLO The lowest dose causing a toxic effect
--------------------------------------------------
Note added at 3 hrs (2010-02-27 18:24:21 GMT)
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http://www.ccohs.ca/oshanswers/chemicals/ld50.html
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