Glossary entry

German term or phrase:

orale Spaltbildung

English translation:

oral cleft formation

Added to glossary by Marga Shaw
Feb 23, 2010 12:34
14 yrs ago
5 viewers *
German term

orale Spaltbildung

German to English Medical Medical: Pharmaceuticals
Glukokortikoide zeigten in Tierversuchen nach systemischer Gabe embryotoxische und terato-gene Wirkungen (z. B. Gaumenspalten, Skelettanomalien, sowie intrauterine Wachstumsstörungen und Embryoletalität). Auch bei menschlichen Feten wird ein erhöhtes Risiko für orale Spaltbildungen bei der systemischen Anwendung von Glukokortikoiden während des ersten Trimenons diskutiert

(Are these the same as Gaumenspalte?)
Proposed translations (English)
3 +3 oral cleft formation
4 +1 cleft palate
Change log

Mar 9, 2010 08:50: Marga Shaw Created KOG entry

Proposed translations

+3
2 hrs
Selected

oral cleft formation

orale Spaltbildung = oral cleft formation

Personally, I would choose the more general term of "oral cleft formation" to cover the cleft palate (Gaumenspalte) and cleft lipe (Lippenspalte) which can occur separately or together.

e.g.:
Cleft lip (CL) and cleft palate (CP) are common developmental conditions. Each can occur either by itself or in conjunction with the other (CL/P). Clefts involve failure of normal structures to properly unite together. The timing of cleft formation occurs very early in embryonic life. Many misconceptions about clefts exist due to persistence of outdated scientific theories.
http://209.85.229.132/search?q=cache:ro_oka3ilVAJ:www.cardin...

Cleft lip/palate is the fourth most common birth defect in the United States. One out of 700 babies is born with a cleft. Currently, it is not completely understood what determines cleft formation. Most information suggests a combination of both genetic/hereditary factors and environmental factors such as illness, alcohol abuse or nutritional deficiency during pregnancy. Regular prenatal care can help reduce the risks of birth defects.
http://209.85.229.132/search?q=cache:2l5rE9q0-LwJ:www.idph.s...





--------------------------------------------------
Note added at 2 hrs (2010-02-23 15:05:30 GMT)
--------------------------------------------------

Unilateral Cleft Lip
• Forms as a persistent labial groove
• Labial groove should disappear as the
maxillary prom. fuse with merged
medial nasal prominences
• Stretching of epithelium causes tissue
breakdown and cleft formation
• Simonart band: bridge of tissue
spanning the cleft (arrow below)
http://docs.google.com/viewer?a=v&q=cache:e4IDSWHuA8wJ:www.o...

Little information is available to draw any conclusions on the role of these exposures and the risk of oral cleft formation. SUMMARY In summary, some of the ...
http://www.google.com/search?hl=en&as_q=&as_epq=oral cleft f...

Routine use of corticosteroid therapy should be avoided during the first trimester secondary to a potential increased risk of oral cleft formation in the fetus. Corticosteroids should be reserved for treatment of refractory NVP or hyperemesis gravidarum.
http://www.medscape.com/viewarticle/545629_3


Peer comment(s):

agree CArcher
2 hrs
Many thanks CArcher!
agree British Diana
4 hrs
Many thanks Diana!
agree Harald Moelzer (medical-translator)
1 day 43 mins
Many thanks Harald!!
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Selected automatically based on peer agreement."
+1
10 mins

cleft palate

Cleft palate is an almost direct translation
Peer comment(s):

agree Ingeborg Gowans (X) : my first thought exactly
5 mins
thank you, Ingeborg.
Something went wrong...
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search