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Glossary entry

Spanish term or phrase:

TPAE

English translation:

TPAE taper/post-study-emergent adverse events

Added to glossary by Cecilia Paris
Nov 10, 2006 12:42
17 yrs ago
4 viewers *
Spanish term

TPAE

Spanish to English Medical Medical: Pharmaceuticals researcher\'s brochure
Se definió como eventos adversos emergentes post-estudio/por reducción gradual (TPAEs por su sigla en inglés) a los eventos adversos que no se presentaron durante los 7 días previos al período de reducción gradual de la dosis o a eventos que estaban presentes pero que se agravaron durante el período de reducción gradual/post-estudio.


"The possibilities are Endless" obviously does not fit in this context. And I don't think it is a typo for TEAE (Treatment-Emergent Adverse Events).

Thanks for your help.
Proposed translations (English)
4 +1 post-[clinical]study adverse drug events/reactions
5 time to peak aortic enhancement
1 +2 test procedure adverse effects

Discussion

Cecilia Paris (asker) Nov 11, 2006:
I found the following reference http://www.medsafe.govt.nz/Profs/Datasheet/e/Efexorxrcap.htm which says "In the Social Anxiety Disorder pooled short-term studies, the most common **taper/post-study-emergent adverse events** were dizziness (13%), nausea (7%), insomnia (3%), nervousness (3%) and asthenia (2%). In the 6-month study, the most common taper/post-study treatment emergent adverse events were dizziness (21% and 16%) and nausea (7% and 10%)". To taper means to reduce. So that explains my TPAE!
liz askew Nov 10, 2006:
Good explanation of your translation problem on this site:
http://66.102.9.104/search?q=cache:8EjMYpNejQgJ:www.hc-sc.gc...
Cecilia Paris (asker) Nov 10, 2006:
Sí, esto es dentro del ámbito farmacológico. El texto indica varias veces que TPAE son las siglas en inglés para "eventos adversos emergentes post-estudio/por reducción gradual ". Un poco más de contexto: "Los TPAE más comunes que presentaron los sujetos tratados con XXX (el fármaco) en todos los estudios a corto plazo y en todos los sujetos con una exposición a largo plazo fueron mareos y náuseas.
mónica alfonso Nov 10, 2006:
Hay algunas otras opciones, pero relacionadas con las emisiones o con la botánica; a pesar de queno se contextualiza demasiado la sigla, creo que en este caso es del ámbito médico o farmacológico. ¿O me equivoco?

Proposed translations

+1
2 hrs
Selected

post-[clinical]study adverse drug events/reactions

See:

PDF] Pharmacogenomics: Changing The ParadigmFile Format: PDF/Adobe Acrobat - View as HTML
genomic drug discovery outside the clinical trial limit ... drug response including the occurrence of adverse reactions. Drug Discovery. Drug Therapy ...
www.jhsf.or.jp/intro/BioJapan/Biojapan_A10-2.pdf - Similar pages


[PDF] Safer Medicines ReportFile Format: PDF/Adobe Acrobat - View as HTML
understanding causes of adverse drug reactions with. their own marketed drugs. This may require some ... based and pre and post-clinical toxicity studies ...
www.acmedsci.ac.uk/images/page/PreClini.pdf - Similar pages


Cancer Clinical Trials: The In-Depth Program - National Cancer ...The trial found that high-risk women who took the drug for up to 5 years (an ... Clinical Trials. Post-Clinical Trials. Total Years for Drug Approval ...
www.cancer.gov/clinicaltrials/resources/in-depth-program/pa... - 60k - Cached - Similar pages


[DOC] NATIONAL LEGISLATIVE ASSOCIATION ON PRESCRIPTION DRUG PRICESFile Format: Microsoft Word - View as HTML
(3/3 FDA Week) reports “A Maryland drug importation lawsuit against FDA argues that ... CALIFORNIA BILL WOULD REQUIRE RX FIRMS TO POST CLINICAL TRIAL DATA ...
www.nlarx.org/newsletters/2006/NLARxNewsletter3_8_06.doc - Similar pages

I have found no satisfactory evidence of "TPAE" on UK sites...I did find "ADR/E" = Adverse drug reactions/events
Peer comment(s):
agree Silvia Brandon-Pérez : Pudiera ser 'treatment post adverse effects..."
14 hrs
Something went wrong...
3 KudoZ points awarded for this answer. Comment: "See my note above. I found it based on your answer. Thanks."
33 mins

time to peak aortic enhancement

Journal of Computer Assisted Tomography - Fulltext: Volume 26(2 ... - [ Traduzca esta página ]We compared the time to peak aortic enhancement (TPAE) among Groups A-E. ... Post hoc test revealed statistically significant differences in TPAE between ...
www.jcat.org/pt/re/jcat/fulltext.00004728-200203000-00022.h... -


--------------------------------------------------
Note added at 35 mins (2006-11-10 13:18:06 GMT)
--------------------------------------------------

Contrast-enhanced CT with saline flush technique using two ... - [ We compared the time to peak aortic enhancement(TPAE) among Groups A-E. ... Post hoc test revealed statistically significant differences in TPAE between ...
cat.inist.fr/?aModele=afficheN&cpsidt=13567122
Something went wrong...
+2
1 hr

test procedure adverse effects

si tp fuera para test procedure
Peer comment(s):
agree mónica alfonso : Sí, seguramente. Ahora que se amplió la pregunta está claro que es así.
5 mins
agree Hebe Martorella : pienso que es correcto
15 mins
Something went wrong...
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