Glossary entry

French term or phrase:

aromatase

English translation:

aromatase/aromatization

Added to glossary by Jonathan MacKerron
Nov 17, 2002 14:52
21 yrs ago
French term

aromatase

French to English Medical
"Se souvenir ici que les androgenes se convertissent aisement en estrogenes grace par example a l'aromatase du tissue grasseux"

"with the help of the aromatase/aromatization of fatty tissue"?

Proposed translations

+1
7 mins
Selected

aromatization

here, I believe

"Estrogen increases in aging men (over 40) in large degree because it is produced from testosterone by a process called aromatization, which occurs particularly in fat cells.

In the aging male: Fat = Estrogen!

Reducing fatty tissue decreases the aromatization of testosterone to estrogen. Certain medications can also reduce aromatization. Testosterone is bound by Sex Hormone Binding Globulin (SHBG) and protein. It is 98% bound and only the free 2% fraction is active. Increasing estrogen levels causes SHBG to increase in the aging male.
"
http://www.google.fr/search?q=cache:HPpdMCIMHNcC:www.antiagi...

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Note added at 2002-11-17 15:03:23 (GMT)
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As far as I see in this sentence it refers to the process, not to the enzyme itself.
Peer comment(s):

agree JCEC
2 mins
merci JCEC !
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4 KudoZ points awarded for this answer. Comment: "Thanks!"
8 mins

aromatization / aromatase expression in ... tissues

I think

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Note added at 2002-11-17 15:03:00 (GMT)
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I\'d also say it\'s ADIPOSE tissue

Role of aromatization of androgens in estrogens and of the ... - [ Traduci questa pagina ]
KU.Leuven Research project, Role of aromatization of androgens in estrogens
and of the, estrogen receptor for the male skeleton. ...
cwisdb.cc.kuleuven.ac.be/research/ P/3M98/project3M980038.htm - 6k - Copia cache - Pagine simili



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Note added at 2002-11-17 15:04:07 (GMT)
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I\'d also say TISSUE, singular

e-Estrogens.com: biochemistry, physiology, female characteristics ... - [ Traduci questa pagina ]
... follicle, corpus luteum or placenta. Estrogens are also produced in
by aromatization of androgens in adipose tissue, liver and skin. ...
Descrizione: Information on biochemistry, synthesis, actions of estrogen. Also, female physiology and oral contracepti...
Categoria: Health > Women\'s Health > Resources
www.e-estrogens.com/ - 17k - 16 Nov 2002 - Copia cache - Pagine simili

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Note added at 2002-11-17 15:06:00 (GMT)
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these are for \'aromatase expression\' (but here I\'d put aromatization):

CAAT: Workshop Program - [ Traduci questa pagina ]
... in the endoplasmic reticulum that converts androgens into estrogens. ... Brueggemeier
discussed the effects of endocrine disruptors on aromatase expression. ...
caat.jhsph.edu/programs/workshops/ testsmart/endo2/breakout-5.htm - 24k - Copia cache - Pagine simili

[PDF]Local estrogen biosynthesis in males and females
Formato file: PDF/Adobe Acrobat - Versione HTML
... the local level, both androgens and estrogens ... role of locally-produced estrogens
in health ... the thiazolidinediones, inhibit aromatase expression would suggest ...
journals.endocrinology.org/erc/006/0131/0060131.pdf - Pagine simili
[ Altri risultati in journals.endocrinology.org ]


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Note added at 2002-11-17 15:07:13 (GMT)
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sorry for the unrequesrted \'singular\' specification above :)
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13 mins

aromatase inhibitors

I believe, in this context
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4 days

with the help of the aromatase of the adipose tissue

Although it is too late, but I think it is the enzyme and not the process according to the reference from medline:
AU: Cohen,-P-G SO: Med-Hypotheses. 1999 Jan; 52(1): 49-51 During the hypogonadal state, there is a preferential deposition of abdominal adipose tissue. With the increasing fatty-tissue accumulation, there is an increase of aromatase activity that is associated with a greater conversion of testosterone to estradiol (testosterone-estradiol shunt).
Something went wrong...
4 days

with the help of the aromatase of the adipose tissue

Although it is too late, but I think it is the enzyme and not the process according to the reference from medline:
AU: Cohen,-P-G SO: Med-Hypotheses. 1999 Jan; 52(1): 49-51 During the hypogonadal state, there is a preferential deposition of abdominal adipose tissue. With the increasing fatty-tissue accumulation, there is an increase of aromatase activity that is associated with a greater conversion of testosterone to estradiol (testosterone-estradiol shunt).
Something went wrong...
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