... is another possibility.

Not all obese patients respond to drug therapy. An anti-obesity drug should therefore beprescribed for no longer than 12 weeks in the first instance and weight loss should then be measured.
http://www.rcplondon.ac.uk/sites/default/files/documents/ant...

In 1996, xxx launched the anti-obesity drug Redux® (dexfenfluramine), a non-specific serotonin receptor agonist that was used with the stimulant phentermine in a combination commonly known as “fen-phen.”
http://www.athersys.com/Home/ProductCandidates/Treatmentsfor...

However, 4 published trials of orlistat in nearly 4000 patients established orlistat as the medication with the longest and largest database of any antiobesity drug (5–8). In addition, antiobesity agents facilitate long-term weight maintenance and lifestyle changes such as a lower fat intake (10), intake of more vegetables and fruit (1, 2, 10), and more physical activity (10); the benefits may far outweigh the potential risks.
http://ajcn.nutrition.org/content/71/3/844.2.full