Aug 8, 2017 14:14
6 yrs ago
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English term
Russian Federation
10+ years of experience in Pharma
Native in: Russian (Variant: Standard-Russia)
Works in: English to Russian, Russian to English
‘average’ and ‘constant’ dosing
English to Russian
Medical
Medical: Pharmaceuticals
Exposures in the All RA population are provided for ‘average’ and ‘constant’ dosing to assign patients to a dose in addition to the whole ХХХХ group which included all exposure regardless of dose.
Proposed translations
(Russian)
| 3 +3 | средняя доза и постоянная доза |
Ann Nosova
|
Proposed translations
+3
1 hr
Ann Nosova
United States
United States
Native in Russian
Specializes in field
United States
Physician,scientist, translator
Native in: Russian 
, Ukrainian
Works in: English to Russian, English to Ukrainian, Russian to English, and 1 more.
Related KudoZ points
:
209
Selected
средняя доза и постоянная доза
Насколько я понимаю (судя по нижеприведенной ссылке), в первом случае назначали дозу на основании расчетов (описанных в Вашем другоа вопросе). Эта доза могла отличаться от той, которую пациент получал раньше (быть выше или ниже). А во втором случае дозу препарата назначали без учета ранее принимаемой (или не принимаемой) дозы.
http://ard.bmj.com/content/annrheumdis/early/2017/01/31/annr...
Dose was categorised using two methods. The primary analysis used the average dosing algorithm in which patients were assigned to average tofacitinib 5 or10 mg twice daily if the average daily dose at end of enrollment
up to the cut-off date was <15 or15 mg, respectively. The constant dosing algorithm was used in a sensitivity analysis. Only patients exposed to a constant tofacitinib dose of 5 or10 mg twice daily without prior exposure to a different tofacitinib dose or adalimumab were included in the algorithm.
http://ard.bmj.com/content/annrheumdis/early/2017/01/31/annr...
Dose was categorised using two methods. The primary analysis used the average dosing algorithm in which patients were assigned to average tofacitinib 5 or10 mg twice daily if the average daily dose at end of enrollment
up to the cut-off date was <15 or15 mg, respectively. The constant dosing algorithm was used in a sensitivity analysis. Only patients exposed to a constant tofacitinib dose of 5 or10 mg twice daily without prior exposure to a different tofacitinib dose or adalimumab were included in the algorithm.
4 KudoZ points awarded for this answer.
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