Mar 15, 2018 09:49
6 yrs ago
1 viewer *
Spanish term
sesgadas
Spanish to English
Medical
Medical (general)
study samples
Hello,
I would appreciate some help with "sesgadas".
Basically this involves a mix up with patient numbers. A patient was inadvertently given the incorrect initials by the local laboratory when examining their samples.
I thought this just meant "incorrect", but it seems to mean something else. The MT put "biased initials" but this doesn't convince me, especially as I couldn't find this on any medical site.
El Investigador colocará una nota en cada historia clínica en la cual se registrará las iniciales sesgadas que corresponde a cada paciente el día 14Mar2018.
Thank you!
I would appreciate some help with "sesgadas".
Basically this involves a mix up with patient numbers. A patient was inadvertently given the incorrect initials by the local laboratory when examining their samples.
I thought this just meant "incorrect", but it seems to mean something else. The MT put "biased initials" but this doesn't convince me, especially as I couldn't find this on any medical site.
El Investigador colocará una nota en cada historia clínica en la cual se registrará las iniciales sesgadas que corresponde a cada paciente el día 14Mar2018.
Thank you!
Proposed translations
(English)
References
sesgadas | Veronica Allievi |
Proposed translations
+2
24 mins
Selected
biased initials
The term iniciales sesgadas means the initials are NOT randomly assigned to the sample but the initials correspond to the patient, thus the researcher can match the sample to the research subject therefore introducing an element of bias in the selection
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Note added at 1 hr (2018-03-15 11:36:35 GMT)
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The random assignment of subjects to one or another of two groups (differing only by the intervention to be studied) is the basis for measuring the marginal difference between these groups in the relevant outcome. Randomisation should equally distribute any confounding variables between the two groups, although it is important to be aware that differences in confounding variables may arise through chance.
Randomisation is one of the cornerstones of the RCT7 and a true random allocation procedure should be used. It is also essential that treatment allocations are concealed from the investigator until recruitment is irrevocable, so that bias (intentional or otherwise) cannot be introduced at the stage of assigning subjects to their groups.8 The production of computer generated sets of random allocations, by a research support unit (who will not be performing data collection) in advance of the start of the study, which are then sealed in consecutively numbered opaque envelopes, is an appropriate method of randomisation. Once the patient has given consent to be included in the trial, he/she is then irreversibly randomised by opening the next sealed envelope containing his/her assignment. (mj.bmj.com/content/20/2/164)
I think Liz, that biased initials in this context is a term applied to the samples before they were randomized, at which time they would be randomly assigned initials again.
--------------------------------------------------
Note added at 1 hr (2018-03-15 11:36:35 GMT)
--------------------------------------------------
The random assignment of subjects to one or another of two groups (differing only by the intervention to be studied) is the basis for measuring the marginal difference between these groups in the relevant outcome. Randomisation should equally distribute any confounding variables between the two groups, although it is important to be aware that differences in confounding variables may arise through chance.
Randomisation is one of the cornerstones of the RCT7 and a true random allocation procedure should be used. It is also essential that treatment allocations are concealed from the investigator until recruitment is irrevocable, so that bias (intentional or otherwise) cannot be introduced at the stage of assigning subjects to their groups.8 The production of computer generated sets of random allocations, by a research support unit (who will not be performing data collection) in advance of the start of the study, which are then sealed in consecutively numbered opaque envelopes, is an appropriate method of randomisation. Once the patient has given consent to be included in the trial, he/she is then irreversibly randomised by opening the next sealed envelope containing his/her assignment. (mj.bmj.com/content/20/2/164)
I think Liz, that biased initials in this context is a term applied to the samples before they were randomized, at which time they would be randomly assigned initials again.
Note from asker:
Strange how I can't find this on any English medical site - do you have any references? Thank you! |
4 KudoZ points awarded for this answer.
Comment: "Thanks!"
3 hrs
skewed initials
sesgo = skewness in statistics
sesgado = skewed in statistics, like a skewed distribution
http://www.statisticshowto.com/probability-and-statistics/sk...
sesgado = skewed in statistics, like a skewed distribution
http://www.statisticshowto.com/probability-and-statistics/sk...
Note from asker:
Yes, I had considered this - just waiting to hear back from the client.. |
5 hrs
Spanish term (edited):
iniciales sesgadas
patient initials
Creo que sesgadas está simplemente mal utilizado aquí, en una frase con varios problemas gramaticales adicionales. Lo interpreto en todo caso, tal y como sugiere George, como alusión a una identificación positiva de cada paciente mediante inclusión de las iniciales correspondientes a cada uno.
Refrasearía y aludiría a (patient positive identification) patient initials.
Refrasearía y aludiría a (patient positive identification) patient initials.
+1
5 hrs
not blinded
This idea is based on George's explanation. I found a number of examples of bias associated with blinding in clinical trials. However, "unblinding" means revealing what had been blinded, so it's not the same as failure to blind (=allow bias) in the first place.
https://www.noclor.nhs.uk/active-research/unblinding
Unblinding. Blinding is used in the design of some clinical trials and other research studies **to try to eliminate the bias of expectation** influencing the research findings. ... A blind trial is a trial where the participants do not know which treatment/intervention they have been allocated.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189869/
by A Al-Chalabi - 2011 - Cited by 13 - Related articles
Sep 21, 2011 - Adjustments of plasma lithium levels were carried out by an unblinded observer, and **the patients were not blinded**.
https://www.noclor.nhs.uk/active-research/unblinding
Unblinding. Blinding is used in the design of some clinical trials and other research studies **to try to eliminate the bias of expectation** influencing the research findings. ... A blind trial is a trial where the participants do not know which treatment/intervention they have been allocated.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189869/
by A Al-Chalabi - 2011 - Cited by 13 - Related articles
Sep 21, 2011 - Adjustments of plasma lithium levels were carried out by an unblinded observer, and **the patients were not blinded**.
Peer comment(s):
agree |
Chema Nieto Castañón
: Actually, not blinded patient initials does make sense within the context.
1 day 2 hrs
|
Thank you!
|
1 day 2 hrs
incorrect/wrong/confusing/confounding initials
Hi, Liz.
I think your first idea was right. As Saltasebes says, this seems an inappropriate use of sesgadas. So it means that the investigator/researcher should add a note to the patients' records (note that "patients" is plural) indicating which wrong initials were attributed to each one on 14th March (which may have distorted or biased the results, diagnosis or whatever, so "iniciales sesgadoras" would be more correct). I think this solution covers all cases.
I think your first idea was right. As Saltasebes says, this seems an inappropriate use of sesgadas. So it means that the investigator/researcher should add a note to the patients' records (note that "patients" is plural) indicating which wrong initials were attributed to each one on 14th March (which may have distorted or biased the results, diagnosis or whatever, so "iniciales sesgadoras" would be more correct). I think this solution covers all cases.
Reference comments
1 hr
Reference:
sesgadas
What the protocol instructs, might be the use of a certain "bias" to disguise the identity of patients. This sounds as a protocol step. The situation you describe above may or may not have been the same as the strict application of the protocol in applying the bias. It might have been the case that whoever assigned the initials did it wrongly, either intending or not intending to apply the protocolar bias.
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